Protein Alignment RhoGAP15B and tum

DIOPT Version :10

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 113/533 - (21%)
• Similarity: 191/533 - (35%)
• Gaps: 160/533 - (30%)

  Fly   858 VEDILKEMQNRKAILRERQFQTFLDQEMKTPREMIPLDTI----------TTLQCVSNSRVTDTA 912
            |.|:|:..:|.....|::  ..|| ..:.:.|:...|:.:          :|...:|:..:|.:.
  Fly   101 VADLLRHERNLNNETRDK--LAFL-HTLPSSRKRKSLNAVREDKSYGDINSTGSLLSDLSITHSE 162

  Fly   913 THFYCFEITTSQ---------PKN-----GN-------GAGDAMSSNPNLLMTSSSSGNVKQQRV 956
            ..|  .::.||:         |||     ||       |...:||.      |:.::|..::..|
  Fly   163 DDF--LDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLNGSMSG------TTPTTGKSRRSSV 219

  Fly   957 -----SHLYGVGKESERGVWMQKI-----------LESLTNSLPVKYTCHYYRAG--------WC 997
                 .|...||:.:||.....|:           .||...||||  .....|.|        ..
  Fly   220 GIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPV--IAGNERIGDGLSSTPRRS 282

  Fly   998 YLKNS--------------ITSEWSGTWLVLRKSQRRLIFVSEANGNVEKMDLRKARCIV----- 1043
            .||.:              :.:| |||.|..|...|...|       .:|..||...|:.
  Fly   283 VLKEATAPPLTPVNAMAPHVVAE-SGTPLQHRPLMRNHTF-------SQKTFLRGDNCVQCQKRI 339

  Fly  1044 ------LKESDESIDNLHVESGPMLMIDCPPYAVYMIMSSARETKIWRHIIREVAHNNGFSLGDQ 1102
                  |:..|..: ..|::...:|.:.|.|      .:....||.....:.:.|.    |:...
  Fly   340 RFGAVGLRCRDCPV-RCHIDCRYLLTVSCVP------QTGTPTTKTMTGYVTDFAP----SIAPM 393

  Fly  1103 QLTRYDVPVIVDKCINFVYIHGSMSEGIYRKSGSENSMHKLMSAF-RADAF----NVEITRNEYN 1162
                  :|.::..|:|.:...|....|:||.|.||.....|...| |..|.    |.:|
  Fly   394 ------IPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNTDI------ 446

  Fly  1163 EHDVANVLKRFMRDLPERLL--GKLTDSFVFVTELAVASEKIPIYRELLAR----LSAIERETLR 1221
             :.:...:|.|:|.|.|.|:  .:..|   |..  ||.:......:::|.:    |....|:||.
  Fly   447 -YVLCCCVKDFLRSLTEPLIPTSQWKD---FAN--AVQNPDTKTAQDMLVKSVKQLPQANRDTLA 505

  Fly  1222 RIVGHLVFISSQQAKNKMSVQNLTMIWGPTLLAKKSDELIYSQKEADVLSDLVVLYKNLFPCSAD 1286
            .::.|...| :|.....|.:.|:::|:|||::.       ||..:.|..:    :|..:|
  Fly   506 FLILHFQRI-AQCPVVLMPIDNISLIFGPTIVG-------YSTPDPDQHA----IYTEVF----- 553

  Fly  1287 EIKREQAMLACLQ 1299
              .::|.|.|.|:
  Fly   554 --TQKQVMKALLE 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850	44/192 (23%)
		RA_ARAPs	1315..1416	CDD:340633
tum	NP_610912.2	C1_MgcRacGAP	317..369	CDD:410371	11/59 (19%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	51/225 (23%)