Protein Alignment RhoGAP15B and Agfg1

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_001129068.1
• Gene: Agfg1 / 363266
• RGDID: 1560041
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 471
• Identity: 98/471 - (20%)
• Similarity: 134/471 - (28%)
• Gaps: 154/471 - (32%)

  Fly    68 KLILQENNSDSQQPIYGPDANENVQEPVYA------------TPRPAPRQRL----PPA-----G 111
            |..|||.....:.  |.|.....|...|:|            ||...|.:.|    .||     |
  Rat   114 KEFLQEKYEKKRW--YVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKG 176

  Fly   112 EPEDSYPDPDDEVPLRILRAAPQIPPKPLNILLDQRSSICSEVSTTSVQTPGKADEDREGSRYAS 176
            .|..|        |:.......|...|..::|.|..|.|.:..:..|..|...|:.....|..|.
  Rat   177 TPTQS--------PVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQ 233

  Fly   177 N------ASLDC----SESSHSGKF--KSQSP-------GYVDAVDSSIPQSDHPDPNGHHPQAE 222
            |      |:.|.    |.||:.|.|  .|.||       |...:|:::....|: .|........
  Rat   234 NSANAEFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAGSVNANFAHFDN-FPKSSSADFG 297

  Fly   223 SSSAEQS---------------------------------SGSQDGDDDNNLLRSLGTTSKL-LG 253
            |.|..||                                 |..|.||..:    ..|||.|. :|
  Rat   298 SFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGS----GFGTTGKAPVG 358

  Fly   254 EAIGERITFKAKGAK----KRLDRNFKSSTEAISNIGADAGRSLKHASKRFGSNFSLGRNKDKAD 314
            ..:.......|...|    ..||..|.|:  |.||   :|..|..:||........:|.:.....
  Rat   359 SVVSVPSHSSASSDKYAALAELDSVFSSA--ATSN---NAYTSTSNASSSVFGTVPVGASPQTQP 418

  Fly   315 IGIGGRPGGSGEMDLDRRQTMPSTEVFNTIQFSSPLNRNGGLPDLRENDAKLQKEDYLRPDPDQE 379
            ...|..|.|:          .|||..|  :..:.|...:...|
  Rat   419 ASSGPAPFGA----------TPSTNPF--VAATGPSAASSTNP---------------------- 449

  Fly   380 DDGCYEVPKTQGKPPSYDEALRSRPSPSDSPMSRNLAQEAAQLVQLRNQRQLSSSSSNGDESPRL 444
                ::.........::..|..|.|:...:|.                |..|.:|.|...:.|..
  Rat   450 ----FQTNARGATAATFGTASMSMPAGFGTPA----------------QYSLPTSFSGSFQQPPF 494

  Fly   445 P-MPAFP-PPRLSQQP 458
            | ..||| ....||||
  Rat   495 PAQAAFPQQTAFSQQP 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Agfg1	NP_001129068.1	COG5347	8..309	CDD:227651	49/205 (24%)
		ArfGap	14..135	CDD:214518	6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..193		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..451		10/79 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900