Protein Alignment RhoGAP15B and Git2

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: XP_017453834.1
• Gene: Git2 / 304546
• RGDID: 1359708
• Length: 761
• Species: Rattus norvegicus
• Alignment Length: 660
• Identity: 134/660 - (20%)
• Similarity: 210/660 - (31%)
• Gaps: 176/660 - (26%)

  Fly   359 LRENDAKLQKEDYLRPDPDQED--------DGCYEVPKTQGKPPSYDEALRSRPSPSDSPMSRNL 415
            ||.||.   ..|...|||....        |.|..|.::.|:..|....|:..|.|
  Rat     5 LRSNDV---CADCSGPDPSWASVNRGTLICDECCSVHRSLGRHISQVRHLKHTPWP--------- 57

  Fly   416 AQEAAQLVQLRNQRQLSSSSSNGDESPRLPMPAFPPPRLSQQPEQFRMDALQPPVRQKRRKNYEH 480
                ..|:|:     :.:..|||..|........|...:|.:.:....|.:.|...:..|..|:.
  Rat    58 ----PTLLQM-----VETLYSNGANSIWEHSLLDPASVMSGRRKANPQDKVHPNKAEFIRAKYQM 113

  Fly   481 IE-LRRPPV---DSAQLEELNRAAAAAER----EESLLISAKNAEAETKTPKPERSDSWEFYGED 537
            :. :.|.|.   ||...::|::...::.|    |..|.:.:..|:|....|
  Rat   114 LAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHP-------------- 164

  Fly   538 ENEEEDRDEEQEGSSSPEPLYANQEATYGKLFEMATAGSSRSNVLTPNQVAEQ---QQLA----- 594
               |:........|.:.:.|.|...|.||     |..|:..|:..||...|.|   ::||
  Rat   165 ---EKGSTPLHVASKAGQILQAELLAVYG-----ADPGTHDSSGKTPVDYARQGGHRELAERLVE 221

  Fly   595 ---CITEDSELDACEGAVGGVP---------LPQAVIEEFDPLSSKCSTLARSNKSNELLLLEHL 647
               .:|:......|    |..|         :||.....   ||...|.||::.|.....|..||
  Rat   222 IQYELTDRLAFYLC----GRKPDHKNGQHFIIPQMADRR---LSLDLSELAKAAKKKLQSLSNHL 279

  Fly   648 LEE---DTYGTVKAEQDDVSMCTSEEEPTTSAATSPKPQQPQ------------------IVHQN 691
            .||   |.|..|...:.|.....::...|....|:..|..|.                  ..|:.
  Rat   280 FEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEF 344

  Fly   692 ARLLSDSMENMLDSDQERAKPYLSRMPESANKASGPVDLASASRNRTNWFVPDKASC-----SDV 751
            |.|:.|.:.   |:.:.:....|||..::.......|....::.::.| ..||..|.     :||
  Rat   345 ATLVIDILS---DAKRRQQGSPLSRSKDNVELILRTVSNQHSTESQDN-DQPDYDSVASDEDTDV 405

  Fly   752 TPNTSKTTPPIE-----GDSPPTYLE------AIGGSK-----------DAAGN--------QEN 786
            ....|:|.....     .|.|.|..|      |:..|:           :.:|.        |..
  Rat   406 ETRASRTNRQKSLDSDLSDGPVTVQEFMEVKHALVASEAKRQQLMKVNNNLSGELRIMQKKLQTL 470

  Fly   787 RSTIGSRFRQTINAISNVKLKMD--------AMKRKASFRGAN--------------------QR 823
            :|...|..||...:...|:...|        ::||:.|.||:.                    ..
  Rat   471 QSENSSLRRQATASACQVQTASDHKDTVSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANH 535

  Fly   824 QSDVRVALQMVPRPSLSPLLIRYEGPLVRFPSGVVEDILKEMQNRKAILRERQFQTFLDQEMKTP 888
            ..:.|..||..|.......|:.....|..|||.:  ...::...|:|...|:|..|.......|.
  Rat   536 PEESRTRLQPFPTHIGRSALVTSSSSLPSFPSTL--SWSRDESTRRASRLEKQNSTPESDYDNTA 598

  Fly   889 REMIPLDTIT 898
            .:..|.||::
  Rat   599 YDPEPDDTVS 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Git2	XP_017453834.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900