DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP15B and Adap1

DIOPT Version :9

Sequence 1:	NP_573183.2	Gene:	RhoGAP15B / 32686	FlyBaseID:	FBgn0030808	Length:	1552	Species:	Drosophila melanogaster
Sequence 2:	NP_766311.2	Gene:	Adap1 / 231821	MGIID:	2442201	Length:	374	Species:	Mus musculus

Alignment Length:	145	Identity:	35/145 - (24%)
Similarity:	60/145 - (41%)	Gaps:	42/145 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 SDSPMSRNLAQEAAQLVQLR----NQRQLSSSSSNGDESPRLPMPAFPPPRLSQQP--------- 458
            |.|.:.||:.| .:::..:|    ::.|:...:|:|:|:.|....:..|| ...:|
Mouse    43 SCSGIHRNIPQ-VSKVKSVRLDAWDEAQVEFMASHGNEAARATFESKVPP-FYYRPTFSDCQLLR 105

  Fly   459 EQFRMDALQPPVRQK-RRKNYEHIELRRP-------------PVDSAQLEELNRAAAAAEREESL 509
            ||:        :|.| .|:.:.|:|.:.|             ..|:.|.  |:|.....|||.:|
Mouse   106 EQW--------IRAKYERQEFVHVEKQEPYSTGYREGLLWKRGRDNGQF--LSRKFVLTEREGAL 160

  Fly   510 LISAKNAEAETKTPK 524
            ....||   :.|.||
Mouse   161 KYFNKN---DAKEPK 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Adap1	NP_766311.2	ArfGap	10..126	CDD:214518	21/92 (23%)
		PH1_ADAP	130..238	CDD:270072	13/48 (27%)
		PH2_ADAP	252..357	CDD:241282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900