Protein Alignment RhoGAP15B and git-1

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_509761.2
• Gene: git-1 / 181253
• WormBaseID: WBGene00008805
• Length: 670
• Species: Caenorhabditis elegans
• Alignment Length: 819
• Identity: 150/819 - (18%)
• Similarity: 264/819 - (32%)
• Gaps: 260/819 - (31%)

  Fly   150 ICSEV---------STTSVQTPGKADEDREGSRY-----ASNASLDCSESSHSGKFKSQSPGYVD 200
            ||||.         |.:.::...|:..|.|..|.     .||.::....:.:.|..|.|.|
 Worm    37 ICSECFCFHSYLGPSVSYLRHLRKSAWDEEHIRLVHALNTSNTNMIWESALYEGSTKFQKP---- 97

  Fly   201 AVDSSIPQSDHPDPNGHHPQAESSSAE----QSSGSQDGDDDNNLLRSLGTTSKLLGEAIGERIT 261
                 :.|    ||:....|......|    |....:|.|.:|:|.|.|...::
 Worm    98 -----MAQ----DPSHIKEQFVKEKYEKLTFQPKRGKDEDLENSLNRQLIACAR----------- 142

  Fly   262 FKAKGAKKRLDRNFKSSTEAISNIGAD-------AGRSLKHASKRFGSN------FSLGRNKDKA 313
                       .:|...|..:..:|||       .|.:..|.:.|.|::      |..|     |
 Worm   143 -----------SDFAHVTLRLIALGADVNYPDPETGDTALHVAAREGNSNQVELLFLYG-----A 191

  Fly   314 DIGIGGRPG--------GSGEMDLDRRQTMPSTEVFNTIQFSSPLNRNGGLPDLRENDAKLQKED 370
            ||....|.|        .:|...|..|.......||:...|.. .||..   |.:.|      :|
 Worm   192 DIMAPNREGMLPYILARDAGHGQLSHRIYEFFFYVFDRFSFFM-CNRKA---DHKNN------QD 246

  Fly   371 YLRPDPDQEDDGCYEVPKTQGKPPSYDEALRSRPSPSDSPMSR--NLAQEAAQLVQLRNQRQLSS 433
            :..|          ||.:.|....:.|    ||.:.|..|..:  :|.::|.. ..:|.:.:::.
 Worm   247 FFIP----------EVTEKQFLTKTND----SRAAISVLPKGQFFDLCEDAFD-ETVRRENEVNW 296

  Fly   434 SSSNGDESPRLPMPAFPPPRLSQQPEQFRMDALQPPVRQKRRKNYEHIELRRPPVDSAQLEELNR 498
            :.:...::.:.|...|.||    .|:   |.|.:...|||..| :..|:.....:|..
 Worm   297 NMTKWAKTAKGPTNLFLPP----TPQ---MSAARNQRRQKLAK-FTPIQFTILLIDLI------- 346

  Fly   499 AAAAAEREESLLISAKNAEAETKTPKPERSDSWEFYGEDENEEEDRDEEQEGSSSPEPLYANQEA 563
                  :::...|:..|....::.||..|                       .|:..||...:::
 Worm   347 ------KDQKRRITGDNPAPVSEPPKNMR-----------------------KSNDTPLRIMKKS 382

  Fly   564 TYGKLFEMATAGSSRSNVLTPNQVAEQQQLACITEDSELDACEGAVGGVPLPQAVIEEFDPLSSK 628
            .|....|:|....|..:.:.||..|           :.||.....|.     ..::|..:.|||.
 Worm   383 EYADYDEVAGISCSPISGIVPNSQA-----------NTLDESSSRVW-----DELLEMKERLSST 431

  Fly   629 CSTLARSNKSN-ELLLLEHLLEEDTYGTVKAEQDDVSMCTSEEEPTTSAATSPKPQQPQIVHQNA 692
            .:.:....|.| ||..|.|.|                                   |.|.::.|:
 Worm   432 ETMVVTLTKQNEELTKLVHSL-----------------------------------QAQNINLNS 461

  Fly   693 RLLS--DSMENMLDSDQERAKPYLSRMPESANKASGPVDLASASRNRTNWFVPDKASCSDVTPNT 755
            .|::  |.:.|:..::..|..|....:.|:..:...||.:......|.:   .|:
 Worm   462 ELITFRDDLYNLKRTNMTRRMPSPLAIVETPERVMPPVGIQQGFSRRDS---EDR---------- 513

  Fly   756 SKTTPPIEGDSPPTYLEAIGGSKDAAGNQENRSTIGSRFRQTINAISNVKLKMDAMKRKASFRG- 819
                  |:|          ||::..:.:.:.|::...:..:      .|:.:.|:|...:|...
 Worm   514 ------IDG----------GGARWRSNSSDRRNSNDHKLDK------KVERRQDSMMESSSSLSR 556

  Fly   820 -------ANQRQSDVRVALQ--MVPRPSLSPLLIRYEGPLVRFPSGVVEDILKEMQNRKAIL--- 872
                   .|:.:...||..|  .:.|...:.|...:.|.|.....|...||...:.:...||
 Worm   557 SSQNPSCLNREEVKTRVIQQSEKITRHIKTLLQHGHNGNLDMNARGGAHDIACAINSLITILLPY 621

  Fly   873 -RERQFQT------FLDQEMKTPREMIPLDTITTLQCVS 904
             |..:..|      .|:.:..:| .::|:|.:...|.::
 Worm   622 VRHEKIDTLTDAVVLLNAKCNSP-VLMPMDIVDAAQTIA 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
git-1	NP_509761.2	ArfGap	7..127	CDD:214518	21/102 (21%)
		ANK	<122..212	CDD:238125	22/116 (19%)
		Ank_5	152..207	CDD:290568	14/59 (24%)
		ANK repeat	165..197	CDD:293786	9/36 (25%)
		GIT	264..294	CDD:128828	7/30 (23%)
		GIT	326..356	CDD:128828	7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900