Protein Alignment RhoGAP15B and K02B12.7

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_492310.1
• Gene: K02B12.7 / 172643
• WormBaseID: WBGene00010500
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 94/508 - (18%)
• Similarity: 176/508 - (34%)
• Gaps: 144/508 - (28%)

  Fly     8 PAPRRLYPELRPANYENI----EIRRPNSPSNN------INHNNI-KKLNINAENLHGNCAEK-- 59
            |..||:..||||.:..|.    |...|...|.:      :..:.| :.|.::...:.....:|
 Worm     4 PRTRRVLKELRPCDDNNFCFECEANNPQWVSVSYGIWICLECSGIHRSLGVHLSFVRSVTMDKWK 68

  Fly    60 -----KLPSSGQNKL--ILQENNSDSQQPIYGPDANE--NVQEPVYATPRPAPRQRLPPAGE--- 112
                 |:.:.|..|.  .||..          ||..|  .:||...:......|.::....|
 Worm    69 DIELAKMKAGGNRKFAEFLQSQ----------PDYKEKWTIQEKYNSRAAALFRDKVACEAEGRE 123

  Fly   113 -PEDSYPDPDDEVPLRILRAAPQIPPKPLNILLDQRSSICSEVSTTSVQTPGKADEDREGSRYAS 176
             .:.:.|            ||..:||            ....:|:.|..|...:.....||.|..
 Worm   124 WSQSTSP------------AANYVPP------------TLGGMSSQSKPTNKSSGNSSLGSYYGG 164

  Fly   177 NASLDCSESSHSGKFKSQSPGYVDAVDSSIPQSDHPDPNGHHPQAESSSAEQSSGSQDGDDDNNL 241
            |:|.  |:|:..|.:.:|        ||:.......: .|:.|...:|..:..:|:..|
 Worm   165 NSSY--SQSTGDGAYSTQ--------DSNSKYQGFGN-TGYVPNQSNSGDDLLAGAMSG------ 212

  Fly   242 LRSLGTTSKLLGEAIGERITFKAKGAKKRLDRNFKSSTEAISNIGADAGRSLKHASKRFGSNFSL 306
             .|:|.             :..:|||.:        :.....::|..|.:.....|:....|.||
 Worm   213 -LSMGW-------------SMLSKGASQ--------AAAMAKDVGIQAQQKASQLSENVSQNNSL 255

  Fly   307 -GRNKDKA-DIGIGGRPGGSGEMDLDRRQTMPSTEVFNTIQFSSPL-NRNGGLPDLRENDAKLQK 368
             |...:|| ::|.....|      |......||...|:.|...:.. :..||...:..:.::.:.
 Worm   256 FGGVANKASEVGTKSWDG------LSSFVKSPSLNAFSGILAKTGYEDFGGGGGGMSGSSSQNEF 314

  Fly   369 EDYLRPDPDQEDDGCYEVPK--TQGKPPSYDEALRSRPSPSDSPMSRNLAQEAAQLVQLRNQRQL 431
            .|:|:..         .:|:  |:|.....:|.|:    |::...::...:.:.:.||  ::.::
 Worm   315 NDWLKQS---------NLPRGTTEGGDHLSNEELK----PTEPVETKKKKERSVKPVQ--SKEKV 364

  Fly   432 SSSSSNGDES------------------PRL-PMPAFPPPRLSQQPEQFRMDA 465
            ::.:...|:|                  ||| |:.|.||.:..::.:.:..||
 Worm   365 TAENVEDDDSSSTITQFESSFNKPKTTAPRLAPVAAAPPKKKEEKAKGWDDDA 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
K02B12.7	NP_492310.1	ArfGap_ArfGap1	6..121	CDD:350059	24/124 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900