Protein Alignment RhoGAP15B and Agfg1

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: XP_006496493.1
• Gene: Agfg1 / 15463
• MGIID: 1333754
• Length: 577
• Species: Mus musculus
• Alignment Length: 509
• Identity: 91/509 - (17%)
• Similarity: 147/509 - (28%)
• Gaps: 187/509 - (36%)

  Fly   166 DEDREGSRYASN--ASLDCSESSHSGKFKSQSP-------------------------------- 196
            |.|:.|..|.:.  .|..|  :|.||..:..:|
Mouse    31 DCDQRGPTYVNMTVGSFVC--TSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIW 93

  Fly   197 -GYVDAVDSSIPQSDHPDPN--------------------------GHHPQAESSSAEQSSGSQD 234
             |..|...|:||  |..||.                          ..|.....|||..:|.:.:
Mouse    94 LGLFDDRSSAIP--DFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPE 156

  Fly   235 --------GDDDNNLLRSLGTTSK--LLGEAIGERITFKAKGAKKRLDRNFKSSTEAISNIGAD- 288
                    |:....|..:.||.|:  ::|.:.|:      :..||:.|        .:|::|:|
Mouse   157 VKPLKSLLGESAPALHLNKGTPSQSPVVGRSQGQ------QQEKKQFD--------LLSDLGSDI 207

  Fly   289 --AGRSLKHASKRFGSNFS--------LGRNKDKADIGIGGRPGGSGEMDLDRRQTMPSTEVFNT 343
              |......|:..| :||:        ...|.|.|:....|:..||....           .|.|
Mouse   208 FAAPAPQSTATANF-ANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFG-----------GFPT 260

  Fly   344 IQFSS--PLNRNGGLPDLRENDAKLQKEDYLRPDPDQEDDGCYEVPKTQGKPPSYDEALRSRPSP 406
            ...||  |....|....:..|.|....    .|.....|.|.:...::.            :.:.
Mouse   261 ASHSSFQPQTTGGSAGSVNANFAHFDN----FPKSSSADFGTFSTSQSH------------QTAS 309

  Fly   407 SDSPMSRNLA--QEAAQLVQLRNQRQLSSSSSNGDE------SPRLPMPAF--PPPRLSQQPEQF 461
            :.|.:|.|.|  |.|.:...|.|...:.|:...||:      :.:.|:.:.  .|...|...:::
Mouse   310 TVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSHSSASSDKY 374

  Fly   462 RMDALQPPVRQKRRKNYEHIELRRPPVDSAQLEELNRAAAAAEREESLLISAKNAEAETKTPKPE 526
                                         |.|.||:...::|....:......||.:......|.
Mouse   375 -----------------------------AALAELDSVFSSAATSSNAYTPTSNASSSVFGTVPV 410

  Fly   527 RSDSWEFYGEDENEEEDRDEEQEGSSSPEPLYANQEATYGKLFEMATAGSSRSN 580
            .:.:               :.|..||.|.|..|....   ..|..||..|:.|:
Mouse   411 GASA---------------QTQPASSGPAPFGATPST---NPFVAATGPSAASS 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Agfg1	XP_006496493.1	COG5347	8..268	CDD:227651	51/266 (19%)
		ArfGap_AGFG1	13..128	CDD:350082	18/100 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900