Protein Alignment RhoGAP15B and acap3b

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_001076484.1
• Gene: acap3b / 100009646
• ZFINID: ZDB-GENE-070209-274
• Length: 846
• Species: Danio rerio
• Alignment Length: 570
• Identity: 115/570 - (20%)
• Similarity: 186/570 - (32%)
• Gaps: 193/570 - (33%)

  Fly   269 KRLDRNFKSSTEAISNIGADAGRSLKHASKRFGSNFSLGRNKDKADIGIGGRPGGSGEMDLDRRQ 333
            :||||....||.:|.:......|.::                              |:..|.|.|
Zfish   376 ERLDRTASPSTSSIDSASEPRERVVR------------------------------GDSILQRVQ 410

  Fly   334 TMPSTEVFNTIQFSSP-----------------LNRNGGLPDLRENDAKLQKEDYLRPD------ 375
            .:|..|:......|.|                 ::|:.|:...:.....|   |...|:
Zfish   411 CLPGNEICCDCGQSDPRWASINLGILLCIECSGIHRSLGVHCSKVRSLTL---DTWEPELMKLMC 472

  Fly   376 ------PDQEDDGCYEVPKTQGKPPSYDEALRSRPSPSDSPMSRNLAQEAAQLVQLRNQRQLSSS 434
                  .:|..:|..|           ::.|: :|.|:.|...:. |...|:.|:.:..:::..|
Zfish   473 ELGNTVINQIYEGACE-----------EQGLK-KPGPNSSRQEKE-AWIKAKYVERKFLKKMCGS 524

  Fly   435 SS---NGDESPRLPMPAFPPPRLSQQPEQFRMDALQPPVRQKRRKNYEHIELRRPPVDSAQLE-- 494
            .:   .|.:|          ...|.:..:....:::.|   |.|:.|.|        |:|.:.
Zfish   525 EALLEGGRKS----------HHWSVKKCRRHNSSIRAP---KTRRKYRH--------DAAIMSPG 568

  Fly   495 ELNRAAAAAE-REESL--------LISAKNAEAETKTPKPERSDSWEFYGED------------- 537
            .|:.|||||: |.|||        |.|..:..:..::|....|||......|
Zfish   569 NLSAAAAAAKFRRESLFCPDELDSLFSYFDTGSGPRSPAGLSSDSGLGGSTDGSTDILVFGSVVD 633

  Fly   538 ---ENEEEDRDE-------EQEGSSSPEP---------LYANQEATYGKLFEMATAGSSRSNVLT 583
               |.|.||.||       ||| :|.||.         |:....|....:...|.|..:..|.::
Zfish   634 SVTEEECEDSDESSGEVDIEQE-ASDPEDGRELDPNTLLHKASRARNMPVMAEALAHGADVNSVS 697

  Fly   584 PNQVAEQQQLACITEDSELDACEGAV-GGVPLPQAVIEEFDPL---------SSKCSTLARSNKS 638
            ....::...:..:|..| |.|||..: .|..:.|..|....||         ...|..|.|....
Zfish   698 EEDESKSPLIQAVTGGS-LIACEFLLQNGADVNQRDIRGRGPLHHATCLGHTGQVCLFLKRGAGQ 761

  Fly   639 NELLLLEHLLEEDTYGTVKAEQDDVSMCTSEEEPTTSAATSPKPQQPQIVHQNARLLSDSMENML 703
            .|       ::||       .||.:|:       ...||.:......::...|        |.|.
Zfish   762 ME-------VDED-------GQDPLSI-------AVQAANADIVTLLRLARMN--------EEMR 797

  Fly   704 DSDQERAKPYLS------RMPESANKASGPVDLASASRNRTNW--FVPDK 745
            ::|....:|..|      |:...:.:|| |..|:|....|| |  :.|.|
Zfish   798 EADGPLGQPDASVPVSPLRVKRKSLRAS-PRSLSSFGSFRT-WLIYTPPK 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
acap3b	NP_001076484.1	BAR_ACAP3	16..215	CDD:153321
		PH	269..363	CDD:278594
		PH_ACAP	271..367	CDD:270070
		ArfGap	403..520	CDD:279720	22/132 (17%)
		ANK repeat	666..697	CDD:293786	5/30 (17%)
		ANK	668..787	CDD:238125	27/140 (19%)
		Ank_2	671..759	CDD:289560	19/88 (22%)
		ANK repeat	699..732	CDD:293786	8/33 (24%)
		ANK repeat	734..759	CDD:293786	5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910