DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wus and DNAJB14

DIOPT Version :9

Sequence 1:	NP_001285355.1	Gene:	wus / 32683	FlyBaseID:	FBgn0030805	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	90	Identity:	35/90 - (38%)
Similarity:	46/90 - (51%)	Gaps:	19/90 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 VDGE------RNSYKVLGVSATASQAEITAAYRKLSKEYHPDKVKDEGLRAQAHQRFIEIQQAYS 382
            |||.      :|.|:||||:..|...::..|||||:.::||||....|    |...|.:|..||:
Human    97 VDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPG----ATDAFKKIGNAYA 157

  Fly   383 VLSKIKSNRRRKNKQY----QEEEA 403
            |||     ...|.|||    .||:|
Human   158 VLS-----NPEKRKQYDLTGNEEQA 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wus	NP_001285355.1	TM2	47..97	CDD:282945
		DnaJ	327..>385	CDD:223560	23/63 (37%)
		DnaJ	331..385	CDD:278647	22/53 (42%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	32/80 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810