Protein Alignment wus and DNAJC22

DIOPT Version :10

• Sequence 1: NP_573180.1
• Gene: wus / 32683
• FlyBaseID: FBgn0030805
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_079178.2
• Gene: DNAJC22 / 79962
• HGNCID: 25802
• Length: 341
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 110/369 - (29%)
• Similarity: 172/369 - (46%)
• Gaps: 70/369 - (18%)

  Fly    49 KSVVIAYLCWLFGGIFGLHHLYLHRDRHAFIWWCTLGGYMGIGWMGELFLIPEYVRDAN------ 107
            |.:::.|..|..||..|||||||.||.||.:|..|||| .|:||:.|.:.:|.:|..||
Human     3 KGLLVTYALWAVGGPAGLHHLYLGRDSHALLWMLTLGG-GGLGWLWEFWKLPSFVAQANRAQGQR 66

  Fly   108 EDPKFVKMFVAKLQAYPKPPYSSKRFVGQVMIGHLFGQVCSMAIPETLVGGWDLSFLHWTIPLFV 172
            :.|:.|           .||.|..||..||::|..||.|..:::...      ::|....:||.|
Human    67 QSPRGV-----------TPPLSPIRFAAQVIVGIYFGLVALISLSSM------VNFYIVALPLAV 114

  Fly   173 SLGVWLVGNIGREQGVWWHCLVAAYLAYPARYLIYDETYSLLLTGLVAALTFDGLSKQWRRTPPR 237
            .|||.||..:|.:...:.:.|.:|:|..|   :.|....::|...:.|::|    :::.||....
Human   115 GLGVLLVAAVGNQTSDFKNTLGSAFLTSP---IFYGRPIAILPISVAASIT----AQRHRRYKAL 172

  Fly   238 RGSP--GERTFKLTTAVIIYCAFWGSFLY-----FNGTISDEDGGEVPIHEAIHNFLASAWWT-- 293
            ..|.  ..|.::|..|   |.||.|...|     ...|:|       .:.|...:||  .|::
Human   173 VASEPLSVRLYRLGLA---YLAFTGPLAYSALCNTAATLS-------YVAETFGSFL--NWFSFF 225

  Fly   294 DLKQALLDTYNYAQHHGW-------------YETWKEVFE---SMDVDGERNSYKVLGVSATASQ 342
            .|...|::......:..|             ::.|.:::|   |...:..:.:|:|||:|..|:.
Human   226 PLLGRLMEFVLLLPYRIWRLLMGETGFNSSCFQEWAKLYEFVHSFQDEKRQLAYQVLGLSEGATN 290

  Fly   343 AEITAAYRKLSKEYHPDKVKDEGLRAQAHQRFIEIQQAYSVLSK 386
            .||..:|::|.|.:|||...|:...||.|  |:|||.||.|||:
Human   291 EEIHRSYQELVKVWHPDHNLDQTEEAQRH--FLEIQAAYEVLSQ 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wus	NP_573180.1	TM2	47..97	CDD:428337	25/47 (53%)
		DnaJ	331..393	CDD:395170	27/56 (48%)
DNAJC22	NP_079178.2	DnaJ	278..335	CDD:197617	27/57 (47%)