DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wus and dnajc22

DIOPT Version :9

Sequence 1:	NP_001285355.1	Gene:	wus / 32683	FlyBaseID:	FBgn0030805	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001107370.1	Gene:	dnajc22 / 100135195	XenbaseID:	XB-GENE-5859098	Length:	340	Species:	Xenopus tropicalis

Alignment Length:	374	Identity:	111/374 - (29%)
Similarity:	181/374 - (48%)	Gaps:	69/374 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KSVVIAYLCWLFGGIFGLHHLYLHRDRHAFIWWCTLGGYMGIGWMGELFLIPEYVRDAN-EDPKF 112
            ||::.||..|..||..||:|:||.||.||.:|..||||: |:|||.:.:.||.:|...| ::.|.
Frog     3 KSLLAAYGLWALGGPLGLYHIYLGRDSHALLWMLTLGGF-GMGWMWDFWKIPIHVYKYNRQERKN 66

  Fly   113 VKMFVAKLQAYPKPPYSSKRFVGQVMIGHLFGQVCSMAIPETLVGGWDLSFL---HWTI-PLFVS 173
            :::      ...:||.|..||:|||..|..||.|.::.          ||||   |..: ||.|:
Frog    67 IEV------KEGEPPASPIRFIGQVATGIYFGIVAAIG----------LSFLSSFHMVVLPLAVA 115

  Fly   174 LGVWLVGNIGREQGVWWHCLVAAYLAYPARYLIYDETYSLLLTGLVAALTFDGLSKQWRRTPPRR 238
            |||.||..:|.:.....:.|:||:|..|   :.|....|::...|.|::|    |::..|...::
Frog   116 LGVHLVATVGEQTSDLKNTLIAAFLTSP---IFYGRAVSMIPISLTASIT----SQKHMRYRLQQ 173

  Fly   239 GSPGERTFKLTTAVIIYCAFWGSFLY-----FNGTISDEDGGEVPIHEAIHNFLASAWWTDL--- 295
            ....:.:.:|....::|.||.|...|     .:.|:|...|       :|.:.|.   |..:
Frog   174 EKQEKLSLRLYRIGLVYLAFTGPLAYSALLNTSLTVSYVAG-------SIGSMLE---WLSIFPS 228

  Fly   296 -----KQALLDTYN----------YAQHHGWYETWKEVFE---SMDVDGERNSYKVLGVSATASQ 342
                 ::.||..|.          :..|  :::.|::::|   :...:.|..:.|||||:..::.
Frog   229 ISALVERLLLLPYRVWAVFSGGGVFRDH--YFKEWEKIYEFVATFQSEKEEMACKVLGVNFKSTM 291

  Fly   343 AEITAAYRKLSKEYHPDKVKDEGLRAQAHQRFIEIQQAYSVLSKIKSNR 391
            .||...||:|.|.:|||..:.....||.|  |:|||.||..|.:::.::
Frog   292 EEINRKYRELVKIWHPDHNRHRLEEAQEH--FLEIQAAYETLMRLRKSK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wus	NP_001285355.1	TM2	47..97	CDD:282945	25/47 (53%)
		DnaJ	327..>385	CDD:223560	24/57 (42%)
		DnaJ	331..385	CDD:278647	23/53 (43%)
dnajc22	NP_001107370.1	TM2	1..50	CDD:377473	25/47 (53%)
dnajc22	NP_001107370.1	DnaJ	281..331	CDD:99751	23/51 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10511
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11777
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4454
OMA	1	1.010	-	-		QHG48477
OrthoDB	1	1.010	-	-		D1058581at2759
OrthoFinder	1	1.000	-	-		FOG0007043
OrthoInspector	1	1.000	-	-		oto105272
Panther	1	1.100	-	-	LDO	PTHR44733
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7335
SonicParanoid	1	1.000	-	-		X5919
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110