DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4928 and SPAC922.05c

DIOPT Version :9

Sequence 1:	NP_573179.1	Gene:	CG4928 / 32682	FlyBaseID:	FBgn0027556	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_595005.1	Gene:	SPAC922.05c / 2543555	PomBaseID:	SPAC922.05c	Length:	504	Species:	Schizosaccharomyces pombe

Alignment Length:	541	Identity:	109/541 - (20%)
Similarity:	187/541 - (34%)	Gaps:	147/541 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NAGFENDEPVKPKAGFEPDTASLREK--VVLNPG-EKWRILKNISIISIAFMVQFTAFQGTANLQ 67
            :|..:.::...|:.| |.:||.|.:.  :...|. .:::.|...|.::...:|.:..|.    ..
pombe    15 SADVDVEKAPTPEYG-EVETAPLSQSSWIYRRPRIGRFKSLAYGSALTQTIIVSWVCFL----CP 74

  Fly    68 SSINAKDGLG-------------TVSLSAIYAALVVSCIFLPTLIIRKLTVKWTL---------- 109
            ...||..|||             .|:|.:.:|.|.    |....|...:.||.||
pombe    75 GMFNALSGLGGGGEVNADVANDANVALYSTFAGLG----FFAGSICNLIGVKLTLAIGGTGYSVY 135

  Fly   110 VCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQVGQVYAKITEQAVDAIIVR 174
            ..|:|||.     .::.|.:.:. .|..:|:.|..:||::...:..    |.:  |:.....|..
pombe   136 TASLLCYK-----HVYNRGFVIF-GGCYLGLTAGMLWAAQGAVIMS----YPR--EENKARYIAI 188

  Fly   175 FFGFFFLAWQSAELWGNLISSLV-LSSGAHGGGSSSNTTVSEEDLQFCGANFCTTGSGGHGNLER 238
            |:|.|.|        |.:|.|:| |:...|   ||.|                :.|.|.:.
pombe   189 FWGIFNL--------GAVIGSIVPLAQTMH---SSVN----------------SVGDGTYA---- 222

  Fly   239 PPEDEIFEISMIYLSCIVAAVCIIAFFLDPLKRYGEK------RKGSNSAAELSGL-QLLSATFR 296
                     ..|.|..:.:|:.:  |.:.|.|...|.      .|......||.|| |.|
pombe   223 ---------GFIVLMAVGSALAL--FMVSPEKTVKEDGKFVHIEKSMGWKKELLGLVQTL----- 271

  Fly   297 QMKKPNLQLLIPITVFIGMEQAFIGADFTQAY--------------VACALG------------V 335
             .|:..:.||.|:.........:...||..||              .|..:|            .
pombe   272 -YKEYWVLLLFPMFFSSNWFTTYQFNDFNLAYFNIRTRSLNNLLYWFAQIMGSAVAALFLDWQRF 335

  Fly   336 NKIGFVMICFGVVNALCSILFGS----VMKYIGRTPIIVLGAVVHFTLITVELFWRPNPDNPIIF 396
            |::....:.:|:|..|..:::|.    .:||..:       :|.....:..:...|.......::
pombe   336 NRVIRARVGWGLVFVLICVIWGGGLAFQLKYTRK-------SVAESDFVVTDFTHRGYTGYAFLY 393

  Fly   397 YAMSGLWGVGDAVWQTQINGLYGLLFR-RNKEAAFSN-YRLWESAGFVIAYAYATTLCTQMKLYI 459
            .    .:|:.||::|:....:.|.|.. .||.|.:.. |:..:|||..|.|...|.....|..:.
pombe   394 I----FYGMLDAIFQSYAYWIIGSLSNDTNKLAVYMGFYKSLQSAGAAITYRMDTLNIPYMNYFA 454

  Fly   460 LLAVLTLGCIGYVIVEILYRK 480
            ....|..|.: .|...::::|
pombe   455 SCWALLCGSL-IVASPVIWKK 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4928	NP_573179.1	MFS	49..>155	CDD:328737	27/128 (21%)
CG4928	NP_573179.1	MFS_1	<255..426	CDD:331686	37/208 (18%)
SPAC922.05c	NP_595005.1	MFS_1	99..438	CDD:284993	84/413 (20%)
SPAC922.05c	NP_595005.1	MFS	<101..202	CDD:304372	28/124 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910