DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4928 and plep-1

DIOPT Version :9

Sequence 1:	NP_573179.1	Gene:	CG4928 / 32682	FlyBaseID:	FBgn0027556	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001300605.1	Gene:	plep-1 / 190188	WormBaseID:	WBGene00021797	Length:	456	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	112/511 - (21%)
Similarity:	194/511 - (37%)	Gaps:	142/511 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 NISIISIAFMVQFTA-----------FQG--TANLQSSINAKDGLGTVSLSAIYAALVVSCIFLP 96
            |:..:|.:|::.|:|           |.|  .||: ..|.|:||.  :.|..:|....|||.|.|
Worm    10 NMLRVSTSFLILFSAVLSHEFIAEPLFHGLSEANI-GGIQARDGY--LMLCILYFTNTVSCFFAP 71

  Fly    97 TLIIRKLTVKWTLVCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQVGQVYA 161
             .::.:::.||.:|..|:......|..:||..|.|:....|.|.||..:|..:..|:|:
Worm    72 -FVVSRISGKWAMVLGMVAAFCMQAAYMFPNRYILMVTSALGGAGATLLWVGQGQYITE------ 129

  Fly   162 KITEQAVDAIIVRFFGFFFLAWQSAELWGNLISSLVLSSGAHGG--------GSSSNTTVSEEDL 218
            .|:|...:.             .::..||....||:.     ||        .||.:..|:...:
Worm   130 NISEANREK-------------NTSIQWGFYKMSLIF-----GGVFFFFYFQNSSIDAIVANGQM 176

  Fly   219 QFCGANFCTTGSGGHGNLERPPEDEIFEISMIYLSCIVAAVCIIAFFLDPLKRYGEKRKGSNSAA 283
            |                        ||.|  ::::..|.:: |.:.||       .:.:.|.:.|
Worm   177 Q------------------------IFFI--VFMTFTVLSI-INSIFL-------PQSQVSQNQA 207

  Fly   284 ELSGLQLLSATFRQMKKPNLQLLIPITVFIGMEQAFIGADFTQAYVAC-----ALGVN-----KI 338
            .|...:....:|:.:|.|.:........:.|:.::|    :...|.||     .|..|     .|
Worm   208 ILPFCETFVNSFKLLKTPRMFCFTIFFFYTGLIRSF----WISIYPACIKFTSQLSTNTTAILTI 268

  Fly   339 GFVMI-CFGVVNALCSILFGSVMKYIGRTPIIVLGAVVHFTLITVELFWRPNPDNPI-------- 394
            |.::. |..|:.:|...:.|:.::..|:..:|:...::|..|..:.....|| |.|:
Worm   269 GMIVTGCGQVIGSLSVAVIGNKIRKFGQHTLILCALILHIFLCVMISLTFPN-DAPLGHTDKNGP 332

  Fly   395 IFYA-------MSGLWGVGDAVWQTQINGLYGLLFRRNKEAAFSNYRLWESAG-------FVIAY 445
            :|.|       :|.|.|.|||:.|||:.......::......||.:|.  |:|       |...|
Worm   333 VFGASVLSAMTISALLGFGDAILQTQVYSYIAKYYQNESSTVFSIFRF--SSGIASTLLFFAAQY 395

  Fly   446 AYATTLCTQMKLYILLAVLTLGCIGYVIVEILYRKKQRKLKKQEKLEAAEKEKEAA 501
            .:   |...:.|..:.|||:    |..::..            :|..||..||:.|
Worm   396 FH---LMHHLILIAIFAVLS----GLAVLRF------------QKSSAAVSEKQKA 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4928	NP_573179.1	MFS	49..>155	CDD:328737	34/118 (29%)
CG4928	NP_573179.1	MFS_1	<255..426	CDD:331686	42/196 (21%)
plep-1	NP_001300605.1	UNC-93	14..170	CDD:114686	45/183 (25%)
plep-1	NP_001300605.1	MFS_1	54..388	CDD:284993	85/399 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930