DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4928 and unc93a.2

DIOPT Version :9

Sequence 1:	NP_573179.1	Gene:	CG4928 / 32682	FlyBaseID:	FBgn0027556	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	XP_002931523.1	Gene:	unc93a.2 / 100170165	XenbaseID:	XB-GENE-5800507	Length:	460	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	195/444 - (43%)
Similarity:	287/444 - (64%)	Gaps:	10/444 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LKNISIISIAFMVQFTAFQGTANLQSSINAKDGLGTVSLSAIYAALVVSCIFLPTLIIRKLTVKW 107
            :|||.|:|..|::.||||.|..:||||:|:.:|||..|||.||.||::|.:|:|:::|:|:..||
Frog     4 IKNILIVSFGFLLLFTAFGGLQSLQSSLNSDEGLGVASLSVIYGALIISSVFVPSILIKKIGCKW 68

  Fly   108 TLVCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQVGQVYAKITEQAVDAII 172
            |:|.||.||..|.....:..:|||:|..:::|.|.||:||:|.||||:.|..||:...:....|:
Frog    69 TIVASMCCYITYSLGNFYASWYTLIPTSLILGFGGAPLWAAKCTYLTESGNRYAEKKGKLAKDIV 133

  Fly   173 VRFFGFFFLAWQSAELWGNLISSLVLSSGAHGGGSSSNTTVSEEDLQFCGANFCTTGSGGHGNLE 237
            .::||.|||.:||:.:||||||||:....:..|.::     |..|...||||.|...:.|:|...
Frog   134 NQYFGLFFLIFQSSGVWGNLISSLIFGQDSPAGSNN-----SFPDYSHCGANDCPGSNFGNGTGS 193

  Fly   238 -RPPEDEIFEISMIYLSCIVAAVCIIAFFLDPLK-RYGEKRKGSNSAAELSGLQLLSATFRQMKK 300
             :|.:..|:.:..:|....|.||.:||.|||.:. |..:.:.|:.   |.|.::.:.||.|.:|.
Frog   194 IKPTQSLIYTLLGVYTGSGVLAVILIAVFLDTINLRTDQLKPGTK---EESFIKKILATIRHLKD 255

  Fly   301 PNLQLLIPITVFIGMEQAFIGADFTQAYVACALGVNKIGFVMICFGVVNALCSILFGSVMKYIGR 365
            ....||||:|::.|.||.|:..|:|::||.|:||::.:|:|||||...||:||:|||.:.||.||
Frog   256 KRQCLLIPLTMYSGFEQGFLAGDYTKSYVTCSLGIHFVGYVMICFAATNAVCSLLFGQLSKYTGR 320

  Fly   366 TPIIVLGAVVHFTLITVELFWRPNPDNPIIFYAMSGLWGVGDAVWQTQINGLYGLLFRRNKEAAF 430
            ..:.::.||::...|...|.|:|:|::..:|:....:||:.|||||||.|.|||:||..:|||||
Frog   321 IFLFIMAAVLNAASIIALLLWQPHPNDFAVFFIFPAIWGIADAVWQTQTNALYGVLFDEHKEAAF 385

  Fly   431 SNYRLWESAGFVIAYAYATTLCTQMKLYILLAVLTLGCIGYVIVEILYRKKQRK 484
            :|||||||.||||||.|:|.||..:|||||||||.:..:.|..||.|...:.:|
Frog   386 ANYRLWESLGFVIAYGYSTFLCVSIKLYILLAVLLIAIVLYGCVEYLEYVEHKK 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4928	NP_573179.1	MFS	49..>155	CDD:328737	50/105 (48%)
CG4928	NP_573179.1	MFS_1	<255..426	CDD:331686	72/171 (42%)
unc93a.2	XP_002931523.1	MFS_unc93A_like	7..434	CDD:340964	192/434 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	268	1.000	Domainoid score	I1831
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10356
Inparanoid	1	1.050	394	1.000	Inparanoid score	I1926
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	1	1.000	-	-		FOG0003220
OrthoInspector	1	1.000	-	-		otm49345
Panther	1	1.100	-	-	O	PTHR19444
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2635
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080