Protein Alignment CG4880 and TOR2A

DIOPT Version :10

• Sequence 1: NP_573177.1
• Gene: CG4880 / 32680
• FlyBaseID: FBgn0030803
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_001078816.2
• Gene: TOR2A / 27433
• HGNCID: 11996
• Length: 321
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 55/279 - (19%)
• Similarity: 99/279 - (35%)
• Gaps: 79/279 - (28%)

  Fly   119 DMVLHARHQVLNQDLALNQLE-LALDNTTNEAIVLV--GTSGVGKSHTARILRE----------- 169
            |:..|...|.|.:.|.:..|: ...|....:.:||.  |.:|.|||:.:.:|..
Human    55 DLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPR 119

  Fly   170 --------TFPWPENVNTLSWTGSSSLGRVKSMLSG-LTYCGQNMILIDNMTPKDAHFVPIINEM 225
                    .||.|.::....       ..:||.:.| ||.||:::.|.|.|.......:.::...
Human   120 VHHFSPVLHFPHPSHIERYK-------KDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPF 177

  Fly   226 ISEG--EKSANHTEHPQQKRLTIVFIFNV-------------NSMQPGEEF---EMDMEILR--- 269
            :...  ....|:      ::...:||.|.             .|.:..||.   |::..|.|
Human   178 LGSSWVVYGTNY------RKAIFIFISNTGGKQINQVALEAWRSRRDREEILLQELEPVISRAVL 236

  Fly   270 NMPH--------------TQLVTFATLDPTHLVDCIRREAAIAMVHLEDEHVEEIIKSID----- 315
            :.||              ..:|.|..|...|:..|:..|.|...:...||.|:.::.|..
Human   237 DNPHHGFSNSGIMEERLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPRDEVVQAVLDSTTFFPED 301

  Fly   316 ---ASASGCKSILAKVLLY 331
               .|::|||::.:::..:
Human   302 EQLFSSNGCKTVASRIAFF 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4880	NP_573177.1	P-loop containing Nucleoside Triphosphate Hydrolases	131..>181	CDD:476819	14/71 (20%)
TOR2A	NP_001078816.2	P-loop containing Nucleoside Triphosphate Hydrolases	42..160	CDD:476819	25/111 (23%)