DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DENR and Denr

DIOPT Version :9

Sequence 1:	NP_001259630.1	Gene:	DENR / 32679	FlyBaseID:	FBgn0030802	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_080879.1	Gene:	Denr / 68184	MGIID:	1915434	Length:	198	Species:	Mus musculus

Alignment Length:	173	Identity:	87/173 - (50%)
Similarity:	125/173 - (72%)	Gaps:	10/173 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YPIQMKYCGHCTMPIEYCEYYPEYEKCKEWLELHMPDDFERLKIEE---------EAAAADGTDD 80
            ||:::.|||.|::|.|||||.|:..||::|||.:.|::|.:|.:|.         |.....|.::
Mouse    27 YPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEE 91

  Fly    81 DKKRQKRGGKGLLRVKKKEDVPKRICVSRAARGKKKSVTVVTGLSTFDIDLKVAAKFFGTKFACG 145
            :||:|||||:|.::.||| .||:::.:::..|.|||.||.|.||:||:||||.|.:||..||:||
Mouse    92 EKKKQKRGGRGQIKQKKK-TVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCG 155

  Fly   146 SSVTGDDEIVIQGDVKDDLFDVIPEKWAEIDEDVIEDLGDQKR 188
            :||||:|||:||||..||:.|||.|||.|:|:|.|||||:.|:
Mouse   156 ASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DENR	NP_001259630.1	eIF1_SUI1_like	26..183	CDD:294159	82/165 (50%)
Denr	NP_080879.1	DRP1	28..193	CDD:273472	82/165 (50%)
Denr	NP_080879.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	72..109		11/36 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837964
Domainoid	1	1.000	88	1.000	Domainoid score	I7942
eggNOG	1	0.900	-	-		E1_COG0023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6275
Inparanoid	1	1.050	192	1.000	Inparanoid score	I3854
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55305
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004744
OrthoInspector	1	1.000	-	-		oto92337
orthoMCL	1	0.900	-	-		OOG6_102629
Panther	1	1.100	-	-	LDO	PTHR12789
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5714
SonicParanoid	1	1.000	-	-		X3339
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790