DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DENR and denr

DIOPT Version :9

Sequence 1:	NP_001259630.1	Gene:	DENR / 32679	FlyBaseID:	FBgn0030802	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001002697.1	Gene:	denr / 436970	ZFINID:	ZDB-GENE-040718-450	Length:	208	Species:	Danio rerio

Alignment Length:	208	Identity:	91/208 - (43%)
Similarity:	134/208 - (64%)	Gaps:	23/208 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TNEDVGTNSVADRLQLGPREGVTYPIQMKYCGHCTMPIEYCEYYPEYEKCKEWLELHMPDDFERL 66
            |.|:..:.|..:::.....: ..||:::.|||.|::|.|||||.||..|||:|||.:.||.|.:|
Zfish     3 TTENAESGSPENKVDRADPD-AKYPLKVLYCGVCSLPAEYCEYMPEPAKCKQWLEKNFPDVFAKL 66

  Fly    67 KI----EEEAAAADGTDD-----------------DKKRQKRGGKGLLRVKKKEDVPKRICVSRA 110
            .:    ::|:....|.:|                 :||:|||||:|.::.||| .||:::.:::.
Zfish    67 TLGTAPKQESKGGGGGEDGGGGRGRGEAPPAGEEEEKKKQKRGGRGQIKQKKK-TVPQKVTIAKI 130

  Fly   111 ARGKKKSVTVVTGLSTFDIDLKVAAKFFGTKFACGSSVTGDDEIVIQGDVKDDLFDVIPEKWAEI 175
            .|.|||.||.|.||:||||:||.|.:||..||:||:|||.:|||:||||..||:.|||.|||.|:
Zfish   131 PRAKKKYVTRVCGLATFDIELKEAQRFFAQKFSCGASVTAEDEIIIQGDFTDDIIDVIQEKWPEV 195

  Fly   176 DEDVIEDLGDQKR 188
            |:|.|:|||:.|:
Zfish   196 DDDSIDDLGEVKK 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DENR	NP_001259630.1	eIF1_SUI1_like	26..183	CDD:294159	83/177 (47%)
denr	NP_001002697.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		3/16 (19%)
		eIF1_SUI1_like	26..203	CDD:294159	83/177 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	69..120		14/51 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581761
Domainoid	1	1.000	86	1.000	Domainoid score	I8077
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6275
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3955
OMA	1	1.010	-	-		QHG55305
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004744
OrthoInspector	1	1.000	-	-		oto41548
orthoMCL	1	0.900	-	-		OOG6_102629
Panther	1	1.100	-	-	LDO	PTHR12789
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5714
SonicParanoid	1	1.000	-	-		X3339
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.930