DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DENR and Y47D3A.21

DIOPT Version :9

Sequence 1:	NP_001259630.1	Gene:	DENR / 32679	FlyBaseID:	FBgn0030802	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_499450.1	Gene:	Y47D3A.21 / 176556	WormBaseID:	WBGene00012932	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	103/193 - (53%)
Similarity:	133/193 - (68%)	Gaps:	15/193 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GTNSVADRLQLGPREGVTYPIQMKYCGHCTMPIEYCEYYPEYEKCKEWLELHMPDDFERLKIEEE 71
            |..:|...|..||.:||:||::|.|||.|:||.|||:|..:.:.|:.|...:.|:..|.|:|.:|
Worm     4 GETAVIQSLAPGPIDGVSYPLKMVYCGQCSMPPEYCDYSGQTDVCRAWATQNAPELLEGLEISDE 68

  Fly    72 AAAADGTDDDKKRQKRGGKG-----------LLRVKKKEDVPKRICVSRAARGKKKSVTVVTGLS 125
             .||||  |:||:|||||||           ....|||...|:::.:.|..|| ||||||:.||:
Worm    69 -PAADG--DEKKKQKRGGKGSKTGAAAAQAAASGGKKKGGGPQKVTLQREPRG-KKSVTVIKGLA 129

  Fly   126 TFDIDLKVAAKFFGTKFACGSSVTGDDEIVIQGDVKDDLFDVIPEKWAEIDEDVIEDLGDQKR 188
            |||||||||:|.|..||||||||||.|||||||||||||.|:|||||.::.::.|:||||:||
Worm   130 TFDIDLKVASKLFAQKFACGSSVTGADEIVIQGDVKDDLLDLIPEKWKQVTDEQIDDLGDKKR 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DENR	NP_001259630.1	eIF1_SUI1_like	26..183	CDD:294159	89/167 (53%)
Y47D3A.21	NP_499450.1	DRP1	23..187	CDD:273472	89/167 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159833
Domainoid	1	1.000	100	1.000	Domainoid score	I4414
eggNOG	1	0.900	-	-		E1_COG0023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6275
Inparanoid	1	1.050	197	1.000	Inparanoid score	I2505
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55305
OrthoDB	1	1.010	-	-		D1490022at2759
OrthoFinder	1	1.000	-	-		FOG0004744
OrthoInspector	1	1.000	-	-		oto17621
orthoMCL	1	0.900	-	-		OOG6_102629
Panther	1	1.100	-	-	LDO	PTHR12789
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5714
SonicParanoid	1	1.000	-	-		X3339
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800