DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcp and CRCP

DIOPT Version :9

Sequence 1:	NP_573175.2	Gene:	Rcp / 32678	FlyBaseID:	FBgn0030801	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_055293.1	Gene:	CRCP / 27297	HGNCID:	17888	Length:	148	Species:	Homo sapiens

Alignment Length:	165	Identity:	49/165 - (29%)
Similarity:	85/165 - (51%)	Gaps:	24/165 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METINPTFSYLTNLEVMQILQKIKSTKKK-------FGMRNLATVTYEALQYLEESPCKTQTREN 58
            ||..:...:.|:|.||.|:|..:|..:|:       .|.:||.|:|||.|:|:.::||:.|:.|.
Human     1 MEVKDANSALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCRHQSPEI 65

  Fly    59 IMNYVKDLSSYRLKSQEILQMINDPPTSALHTQLLIDDNKAPLTDEENEKIIQLSYKHFHGGETK 123
            :..::..|.|::|...|.||::|..|.:|:..||::::::..||:|:.|.::..
Human    66 VREFLTALKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHT----------- 119

  Fly   124 GAAKETPAEKPAESTAKAGKQSGVKRNAQAKSNPA 158
             .....|||..||.  |....|.|   |..:.:||
Human   120 -VTSILPAEPEAEQ--KKNTNSNV---AMDEEDPA 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcp	NP_573175.2	RNA_pol_Rpb4	10..112	CDD:281819	36/108 (33%)
CRCP	NP_055293.1	RPOL4c	1..127	CDD:128904	39/137 (28%)
CRCP	NP_055293.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..148		9/28 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154943
Domainoid	1	1.000	77	1.000	Domainoid score	I8906
eggNOG	1	0.900	-	-		E1_KOG4168
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40587
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1634280at2759
OrthoFinder	1	1.000	-	-		FOG0004828
OrthoInspector	1	1.000	-	-		oto90244
orthoMCL	1	0.900	-	-		OOG6_103530
Panther	1	1.100	-	-	LDO	PTHR15561
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3651
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.740