Protein Alignment Nprl2 and nprl-2

DIOPT Version :9

• Sequence 1: NP_573174.1
• Gene: Nprl2 / 32677
• FlyBaseID: FBgn0030800
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_001380165.1
• Gene: nprl-2 / 177532
• WormBaseID: WBGene00018635
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 442
• Identity: 129/442 - (29%)
• Similarity: 215/442 - (48%)
• Gaps: 52/442 - (11%)

  Fly    11 TSTTAGAVTNGAGGSGAGAAGAHGSTEG-KIRCIFLSEFHATAGCKISCQVP-DNYISKDVFDAI 73
            |..|.||.....|.|..|..|.:...:. ::..|.|:|||.|.|..|...|| :|...:..|...
 Worm     7 TLATFGAGPFATGDSSGGRFGHYTFDDAPQLLGILLAEFHNTLGAIIKHSVPKENNKVEATFHFT 71

  Fly    74 NVYIIPKQHLQR--CILTVNAMDVKIVGYPVGIQDQQKYARNAFLFNLCFVCD-SRARSVQYEPV 135
            ...||||..:.|  ..||:.::..|::.:|||| |.:.|.|..|.|::.|:.| :.:....|||:
 Worm    72 KGLIIPKPSMFRNSFSLTIKSLRCKVLMFPVGI-DHKSYERGRFTFDMAFIVDMTSSAETMYEPI 135

  Fly   136 VKKLSEYLIMMEEESCFLSREDDKRRLQNIFETVLRDLNERKVATI---VEGDN--TIYLKI--V 193
            |:|.:||||.:|.|..||:....|.::.::.|.:..||:.:..:.|   :|.:.  |:|.|:  :
 Worm   136 VQKCAEYLIELEMEYKFLTNPKYKDQVLDVMERMFNDLSNKGESVIEVSLEDEKIVTLYFKLCPL 200

  Fly   194 MHKPDPPPVKDHMVPLLL--ANLRDAPLDNWDLTTQQILPYINGINHVARIAAEADVETDLVKSC 256
            ....:||.:..||||:.:  ..|.|..::..|:.:|:|:|.|:|||.|..||...:::..||..|
 Worm   201 YRGCEPPEIDYHMVPMFIREVTLTDHLIEKMDVLSQKIIPQIDGINTVREIAIILELDPSLVARC 265

  Fly   257 IQNLVYYGVVQLLPILKYSNVYM-TQNLKHLIQSASLSGACRKYVALR----------PDKTLPS 310
            ::||.:|..|.|:|:..|.|.|: |:.:....::.:....|.::|.::          |.:| |.
 Worm   266 VRNLHFYECVSLVPMFLYYNTYVATERVHDFYKNQTEINDCLEFVKIQTEIGADGSEIPTRT-PE 329

  Fly   311 VQRIFQFYASM-----------THGVTLRAIC-QRLC-------PQHHNIDERRMVIFGLQHRFI 356
            ...:|:.|.||           :....||..| ..|.       |:...|||:|:|.||:.|:|:
 Worm   330 FSDVFRLYLSMKVVGPKLPIDESDSNRLRFQCGNNLAEWADLEKPRSMGIDEQRLVQFGMHHQFL 394

  Fly   357 RCIHKYPVFTGSVPSGRQ--KMYTGLISFDEICCKTGLSP---CTIERDIEK 403
            |.:.|||:...: |....  |...|..|.||:..:..:.|   |::..:..|
 Worm   395 RKLSKYPICVAN-PGNNTLLKRCNGKTSIDELSLQHNVDPEQLCSLLEETGK 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nprl2	NP_573174.1	NPR3	40..403	CDD:305178	120/410 (29%)
nprl-2	NP_001380165.1	NPR2	37..444	CDD:368796	120/409 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166436
Domainoid	1	1.000	132	1.000	Domainoid score	I3189
eggNOG	1	0.900	-	-		E1_KOG3789
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4771
Inparanoid	1	1.050	161	1.000	Inparanoid score	I2862
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55115
OrthoDB	1	1.010	-	-		D500740at2759
OrthoFinder	1	1.000	-	-		FOG0005663
OrthoInspector	1	1.000	-	-		oto19083
orthoMCL	1	0.900	-	-		OOG6_103955
Panther	1	1.100	-	-	LDO	PTHR12991
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770