DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4872 and AT5G52810

DIOPT Version :9

Sequence 1:	NP_573173.2	Gene:	CG4872 / 32676	FlyBaseID:	FBgn0030799	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_200093.1	Gene:	AT5G52810 / 835358	AraportID:	AT5G52810	Length:	325	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	95/382 - (24%)
Similarity:	155/382 - (40%)	Gaps:	94/382 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSTPAYYNADAVRQVLTW-PLVN------KAVESALVAIVKQNPETPSTSFAFQPKRTFIPCGKE 60
            ::.|.:..|::...:|:. .|:|      ....|.:.:.|:||....|.|
plant     2 AALPVFIPAESFPSILSHETLINHFRTNLPKHSSTITSPVRQNYTVSSPS--------------- 51

  Fly    61 PGKVLLTMPAYVGNYRLESSRDPGEVEHTHSTLACKLVTSFSGNPRRDPPLPSIHAHVLLFDNQT 125
               .||.||::..:..|             ..:..||||.|..|..::  ||.||....||.:.|
plant    52 ---SLLLMPSWSSSSSL-------------PYMGVKLVTYFPHNSSQN--LPGIHGSYTLFSSTT 98

  Fly   126 GQLSAIMEGTDLTTWRTVSASLVATKYLYFRRFGAQAEQERNINVAIVGCGVQGQLHAAAFCANF 190
            ||..|.|:||.||.:||.|.|.:.:|.|        |..:..:.:.:....:...|..:...|..
plant    99 GQTLATMDGTVLTLYRTSSVSGLGSKIL--------ARDDSQVLIMVGSGALAPHLIKSHLAAKP 155

  Fly   191 RVRQLNLYNRTQAKALGLADQL-----RQKLNTESGTQITVCPSPHEACQD----ADIICIATYS 246
            .:|::.::|||..:|..||:.|     .::::.:|          |::...    .|||..||.|
plant   156 SLRRVIIWNRTPQRAQELAETLSKDPQHKEISFDS----------HDSLDQIIPLGDIISCATNS 210

  Fly   247 KEPLIQLADLKSKRAVHINAVGAGEVHFSEVAPKIYQQAKVYVD-CYANAEA-ELVGLPAPITAE 309
            ..||::...||.  ..|::.||:......|......|:..|:|| ..|..|| ||.|     ..|
plant   211 TVPLVKGEFLKP--GTHLDLVGSFSHEMKECDDNAIQRGSVFVDNDTAMIEAGELAG-----AFE 268

  Fly   310 VGQI-----------ILDGNYPKE-----LEISIFQSMGMASEDACVAQAVQDCIIS 350
            .|.|           ::.|:  ||     .:|::|:|:|..:.|...||.|.:..:|
plant   269 RGVIKREDICGNLVELIKGD--KEGRKSSTDITVFKSVGSGTVDLLTAQLVHETYLS 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4872	NP_573173.2	NADB_Rossmann	5..298	CDD:304358	77/310 (25%)
CG4872	NP_573173.2	OCDMu	8..344	CDD:225280	92/369 (25%)
AT5G52810	NP_200093.1	OCD_Mu_crystall	7..324	CDD:332249	94/377 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3535
eggNOG	1	0.900	-	-		E1_COG2423
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1424
Inparanoid	1	1.050	69	1.000	Inparanoid score	I2481
OMA	1	1.010	-	-		QHG60929
OrthoDB	1	1.010	-	-		D1345495at2759
OrthoFinder	1	1.000	-	-		FOG0006383
OrthoInspector	1	1.000	-	-		oto3877
orthoMCL	1	0.900	-	-		OOG6_102950
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740