Protein Alignment CG4872 and CRYM

DIOPT Version :9

• Sequence 1: NP_573173.2
• Gene: CG4872 / 32676
• FlyBaseID: FBgn0030799
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001363185.1
• Gene: CRYM / 1428
• HGNCID: 2418
• Length: 314
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 115/351 - (32%)
• Similarity: 165/351 - (47%)
• Gaps: 51/351 - (14%)

  Fly     3 SSTPAYYNADAVRQVL-TWPLVNKAVESALVAIVKQNPETPSTSFAFQPKRTFIPCGKEPGKVLL 66
            |..||:.:|..|.:.| :..|:...:|:|| |.....||    ....||.||.:|..|..| .|.
Human     2 SRVPAFLSAAEVEEHLRSSSLLIPPLETAL-ANFSSGPE----GGVMQPVRTVVPVTKHRG-YLG 60

  Fly    67 TMPAYVGNYRLESSRDPGEVEHTHSTLACKLVTSFSGNPRRDPPLPSIHAHVLLFDNQTGQLSAI 131
            .||||      .::.|         .|..|||| |..:......:||..|.||||:...|.|.|:
Human    61 VMPAY------SAAED---------ALTTKLVT-FYEDRGITSVVPSHQATVLLFEPSNGTLLAV 109

  Fly   132 MEGTDLTTWRTVSASLVATKYLYFRRFGAQAEQERNINVAIVGCGVQGQLHAAAFCANFRVRQLN 196
            |:|..:|..||.:.|.:|||:|         :...:..:.|:|.|||...|...|...|..:::.
Human   110 MDGNVITAKRTAAVSAIATKFL---------KPPSSEVLCILGAGVQAYSHYEIFTEQFSFKEVR 165

  Fly   197 LYNRTQAKALGLADQLRQKLNTESGTQITVCPSPHEACQDADIICIATYSKEPLIQLADLKSKRA 261
            ::|||:..|...||       |..| ::.||.|..||...||:|...|.:.||:  |.....|..
Human   166 IWNRTKENAEKFAD-------TVQG-EVRVCSSVQEAVAGADVIITVTLATEPI--LFGEWVKPG 220

  Fly   262 VHINAVGAGEVHFSEVAPKIYQQAKVYVDCYANAEAE-----LVGLPAPITAEVGQIILDGNYPK 321
            .|||||||....:.|:..::.::|.:|||....|..|     |.|  |.|.||:|::| .|..|.
Human   221 AHINAVGASRPDWRELDDELMKEAVLYVDSQEAALKESGDVLLSG--AEIFAELGEVI-KGVKPA 282

  Fly   322 ELE-ISIFQSMGMASEDACVAQAVQD 346
            ..| .::|:|:|||.||...|:.:.|
Human   283 HCEKTTVFKSLGMAVEDTVAAKLIYD 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4872	NP_573173.2	NADB_Rossmann	5..298	CDD:304358	93/293 (32%)
		OCDMu	8..344	CDD:225280	111/342 (32%)
CRYM	NP_001363185.1	OCD_Mu_crystall	4..314	CDD:367079	114/349 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154136
Domainoid	1	1.000	108	1.000	Domainoid score	I6477
eggNOG	1	0.900	-	-		E1_COG2423
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1424
Inparanoid	1	1.050	117	1.000	Inparanoid score	I4813
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60929
OrthoDB	1	1.010	-	-		D1345495at2759
OrthoFinder	1	1.000	-	-		FOG0006383
OrthoInspector	1	1.000	-	-		oto90166
orthoMCL	1	0.900	-	-		OOG6_102950
Panther	1	1.100	-	-	LDO	PTHR13812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.810