DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4872 and crym

DIOPT Version :9

Sequence 1:	NP_573173.2	Gene:	CG4872 / 32676	FlyBaseID:	FBgn0030799	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001096532.1	Gene:	crym / 100125176	XenbaseID:	XB-GENE-970817	Length:	313	Species:	Xenopus tropicalis

Alignment Length:	352	Identity:	107/352 - (30%)
Similarity:	162/352 - (46%)	Gaps:	47/352 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PAYYNADAVRQVLTWPLVNKAVESALVAIVKQNPETPSTSFAFQPKRTFIPCGKEPGKVLLTMPA 70
            ||:..|..|.:.|.:..:...:|.||:..     .:.|.....||.||.:|..|..| .|..|||
Frog     5 PAFIGAKVVDKYLDFATLIPLLEKALIHF-----SSGSEGGVVQPIRTIVPVAKYSG-FLGVMPA 63

  Fly    71 YVGNYRLESSRDPGEVEHTHSTLACKLVTSFSGNPRRDPPLPSIHAHVLLFDNQTGQLSAIMEGT 135
            |       |..|        ..|..|:||.:  ..:....:||..|.||||:...|.|.|:::|.
Frog    64 Y-------SKWD--------DALTTKVVTFY--EKKTSSEIPSHQATVLLFEPSNGTLKAVIDGR 111

  Fly   136 DLTTWRTVSASLVATKYLYFRRFGAQAEQERNINVAIVGCGVQGQLHAAAFCANFRVRQLNLYNR 200
            .:|..||.:.|.:|||.|.    .:.||     .:.|:|.|.|.|.|...|...|..:::.:::|
Frog   112 VITDKRTAAVSAIATKLLK----PSHAE-----ILCILGSGAQAQSHYQVFTQQFSFKEVRVWSR 167

  Fly   201 TQAKALGLADQLRQKLNTESGTQITVCPSPHEACQDADIICIATYSKEPLIQLADLKSKRAVHIN 265
            |:.||...|       .|..| ::.||.:|.||...||:|...|.:.||:: ..|. .|...|||
Frog   168 TREKAERFA-------RTAEG-EVHVCSTPQEAVSGADVIITVTMATEPVL-FGDW-VKPGAHIN 222

  Fly   266 AVGAGEVHFSEVAPKIYQQAKVYVD---CYANAEAELVGLPAPITAEVGQIILDGNYPKELE-IS 326
            |:||....:.|:...:.:...:|||   ..|....::|...|.|.||:|: :|.|..|...: .:
Frog   223 AIGACRPDWRELDDVLMESCVLYVDSKEAAAKESGDIVISKASIFAEIGE-VLKGTKPAVTDKTT 286

  Fly   327 IFQSMGMASEDACVAQAVQDCIISSAK 353
            :|:|:|||.||...|:.|.|..::..|
Frog   287 VFKSVGMAVEDTVSAKLVYDSWLAENK 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4872	NP_573173.2	NADB_Rossmann	5..298	CDD:304358	87/294 (30%)
CG4872	NP_573173.2	OCDMu	8..344	CDD:225280	102/339 (30%)
crym	NP_001096532.1	OCD_Mu_crystall	22..312	CDD:367079	101/332 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6739
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1424
Inparanoid	1	1.050	114	1.000	Inparanoid score	I4688
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1345495at2759
OrthoFinder	1	1.000	-	-		FOG0006383
OrthoInspector	1	1.000	-	-		oto103963
Panther	1	1.100	-	-	LDO	PTHR13812
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160