Protein Alignment RSG7 and RGS11

DIOPT Version :9

• Sequence 1: NP_001245722.1
• Gene: RSG7 / 32674
• FlyBaseID: FBgn0024941
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_011521021.1
• Gene: RGS11 / 8786
• HGNCID: 9993
• Length: 499
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 161/484 - (33%)
• Similarity: 238/484 - (49%)
• Gaps: 71/484 - (14%)

  Fly   182 AAQPPQPPTATALAVPSASHHQRGGKNEDAPNILVYKKMEAIIEKMQAESTGVAVRTVKAFMSKV 246
            ||.|..||               |......|::   :|||.::..||....||.:|:.:..::.:
Human     2 AAGPAPPP---------------GRPRAQMPHL---RKMERVVVSMQDPDQGVKMRSQRLLVTVI 48

  Fly   247 PSVFTGADLVAWILKNFDVEDVTEALHFAHLLSSHGYIFPI-DDHALTVKNDGTFYRF------- 303
            |...||:|:|.|:.:.|.|.: .||||...:|..||||:|: |..:|.::.|.|.|||
Human    49 PHAVTGSDVVQWLAQKFCVSE-EEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQEGRRAC 112

  Fly   304 -------------------------QTPYFWPSNCWEPENTDYAVYLCKRTMQNKTRLELADYEA 343
                                     ||||||.|........|||:||.|:.:  :.|..|.|||.
Human   113 WDWSGTPPCRRGLVVHRPLPKSPGPQTPYFWTSTLRPAAELDYAIYLAKKNI--RKRGTLVDYEK 175

  Fly   344 ENLAKLQKMFSRKWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWDVHRPMPGCVNTTEIDIK 408
            :...:|.|..:..|:.:.|||..|.:.||:|.|.:|.|:..||:.:|.|:||.||..:..|
Human   176 DCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLE---- 236

  Fly   409 KAYRRGGSSHGTGSAGAS--LAKNPVEQLTRIIALRKQKLERRTIKVSKAAEALVAYYDQYNEFD 471
                   ...|.||..||  |.....:...|.|...::.|.|..:|.|...||.:::..|....|
Human   237 -------QGPGRGSCAASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHD 294

  Fly   472 YFITSPELPNPWQTDSTEMWDTEKNSKEVPVR-RVKRWAFSLRELLNDAIGREQFTKFLEKEYSG 535
            ..::.....|||.:|:...|.....:...|.: ||:||.||.||||.|.:||..|..||.||:||
Human   295 PLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSG 359

  Fly   536 ENLKFWESVQEMKALPQSEIKEAIQKIWQEFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCF 600
            |||.|||:.:|::...|:::...:..::::||||.|...||:||:::|...|.:..   |:|:..
Human   360 ENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQ---PHRYVL 421

  Fly   601 DVAASHVYHLMKSDSYSRYLRSDMYKDYL 629
            |.|..|:|.|||.|||.|:|:|||||..|
Human   422 DDAQLHIYMLMKKDSYPRFLKSDMYKALL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897	34/119 (29%)
		GGL	432..493	CDD:128520	15/60 (25%)
		RGS_R7-like	504..627	CDD:188660	57/122 (47%)
RGS11	XP_011521021.1	DEP_RGS7-like	24..106	CDD:239897	29/82 (35%)
		GGL	255..316	CDD:128520	15/60 (25%)
		RGS_RGS11	327..452	CDD:188694	59/127 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D201579at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101587
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720