Protein Alignment RSG7 and grid2ip

DIOPT Version :10

• Sequence 1: NP_523380.2
• Gene: RSG7 / 32674
• FlyBaseID: FBgn0024941
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_012826769.3
• Gene: grid2ip / 780069
• XenbaseID: XB-GENE-981804
• Length: 1275
• Species: Xenopus tropicalis
• Alignment Length: 713
• Identity: 117/713 - (16%)
• Similarity: 208/713 - (29%)
• Gaps: 249/713 - (34%)

  Fly    10 KTQATNASSTAAPA--------------KTDCTSSNSSDPLAVAIPEPQSATAVVGGGAGGAAPG 60
            |..|..|...|.|.              .:......|||..:.|..||......|..|...|..|
 Frog   560 KAAAVEAEMVAPPRGSVHGLTSYQSIIHSSGTEDGRSSDSSSGAPCEPVEIAPRVTSGERQAGDG 624

  Fly    61 TATP-SPTPLANGS----------NNGTGSSVSPAATGTGAVATAA------------------- 95
            |:.| :|.|....:          ||..|...|..:.|:..::..|
 Frog   625 TSLPETPNPKMMSAVYAELENRFLNNFQGKVSSMKSHGSCNLSQRAGRGQRRLAQGPLWQRTGPP 689

  Fly    96 SAPAAAGTTSASPPASNPTTASTS-TASVVGAKTAAATTTSSSSATSSST---AAAGSKQSGS-- 154
            |.|......||..|:|:.:....| ..|:..:.:.....|.|.::.|..|   ..|.|:|.|.
 Frog   690 SEPCPPRPPSAPSPSSSESNPYVSLDGSLPSSPSHRKIFTFSRASRSRDTDRFLDALSRQLGQNL 754

  Fly   155 --SGGLLTVSGNHHHHHHAHPQQ-------SAAGQSAA----------------------QPPQP 188
              :...:|...::........|.       |.|.:||:                      .||.|
 Frog   755 TFTDQFMTPENDYEEMSFQDDQYSCATRDISTASESASSSEDGSSLTYSSVSDLVPPPPHSPPPP 819

  Fly   189 PTATALAVPSASHHQRGG------KNEDAPNILVYKKMEAI------------------------ 223
            |.      ||..|..||.      ::..|||..:..|..:.
 Frog   820 PP------PSQPHPSRGDIKPPPEESNAAPNSFMRSKKSSANPLPPAPPPLPNPLIPPAPPLAPL 878

  Fly   224 ---------------IEKMQAESTGVAVRTVKAFMSKVPSVFTGADLVAWILKNFDVEDVTEALH 273
                           :::::.|....:..|:...:.:.......:|:|    |..|:|     ||
 Frog   879 THRNMHRRSDSSHMSVKRLRWEQVENSEGTIWGQLGEDSDYEKLSDMV----KYLDLE-----LH 934

  Fly   274 FAHLLSSHGYIFPIDDHALTVKNDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKTRLEL 338
            |                       ||    |.|...|              :...:|:.|..:|:
 Frog   935 F-----------------------GT----QKPSLLP--------------VLPESMKKKGAVEI 958

  Fly   339 ADY-EAENLAKL---QKMFSRKWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWDVHRPMPGC 399
            ..: :|.|.|.|   .|:...:...|.|..|::........:|.....|.:||..::.:...|..
 Frog   959 LSHKKAYNTAILIAHLKLTPSELRHILMIMENERLEPSHIKQLLLFAPDEEERQQFEAYMGSPNK 1023

  Fly   400 VNTTEIDIKKAYRRGGSSHGTGSAGASLAKNPVEQLTRIIALRKQKLERRTIKVSKAAEALVAYY 464
            ::..:                 .....:...|..::.....|.|..|:.:|.::..:.:.::.
 Frog  1024 LSEPD-----------------QFALQMMSVPEYKMRLRSLLFKSTLQEKTEEIRASCDCILK-- 1069

  Fly   465 DQYNEFDYFITSPELPNPWQTDSTEMWDTEKNSKEVPVRRVKRWAFSLRELLNDAIGREQFTKFL 529
                      .|.||               ||||:  :.::..:..::...|||...:...|
 Frog  1070 ----------ASSEL---------------KNSKK--LAKILEFVLAMGNYLNDGQPKTNRT--- 1104

  Fly   530 EKEYSGENLKFWESVQEMKALPQS-----EIKEAIQKIWQEFLA-----PEAPCPVNVDSKSV 582
                :|..:.|...:...|.:...     .:.:::.:.:.|.|:     |..|....|:.:||
 Frog  1105 ----TGFKINFLTELNTTKTVDGKFTFLHILAKSLSQHFPELLSFAKDLPTVPLAAKVNQRSV 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_523380.2	DEP_RGS7-like	222..309	CDD:239897	14/125 (11%)
		RGS_DHEX	306..407	CDD:375589	18/104 (17%)
		GGL	432..493	CDD:128520	7/60 (12%)
		RGS_R7-like	504..627	CDD:188660	14/89 (16%)
grid2ip	XP_012826769.3	PDZ1_L-delphilin-like	42..117	CDD:467225
		degP_htrA_DO	<53..183	CDD:273938
		harmonin_N_like	225..301	CDD:448372
		PDZ2_L-delphilin-like	369..443	CDD:467226
		HN_L-delphilin-R2_like	478..557	CDD:259821
		FH2	884..1252	CDD:396655	57/383 (15%)