DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RSG7 and Rgs18

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_075019.1	Gene:	Rgs18 / 64214	MGIID:	1927498	Length:	235	Species:	Mus musculus

Alignment Length:	183	Identity:	57/183 - (31%)
Similarity:	97/183 - (53%)	Gaps:	9/183 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   445 KLERRTIKVSKAAEALVAYYDQYNEFDYFITSPELPNPWQTDSTEMWDTEKNSKEVPVRRVKRWA 509
            ||...:.|...:.||.:...::.|.....:..|:.....|...:.:  ..|.::..|...|| ||
Mouse    23 KLMHGSGKEETSIEAKIRAKEKRNRLSLLLQRPDFHGETQASRSAL--LAKETRVSPEEAVK-WA 84

  Fly   510 FSLRELLNDAIGREQFTKFLEKEYSGENLKFWESVQEMKAL--PQSEIKEAIQKIWQEFLAPEAP 572
            .|..:||:...|.:.||:||:.|:|.||::||.:.::.|..  ||..|.:| :.|:::|:..:||
Mouse    85 ESFDKLLSHRDGVDAFTRFLKTEFSEENIEFWVACEDFKKCKEPQQIILKA-KAIYEKFIQNDAP 148

  Fly   573 CPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMY 625
            ..||:|..:.|:..:::   :.|....||.|.|.||.||:.|||.|:|:|:.|
Mouse   149 KEVNIDFHTKEVIAKSI---AQPTLHSFDTAQSRVYQLMEHDSYKRFLKSETY 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897
		GGL	432..493	CDD:128520	8/47 (17%)
		RGS_R7-like	504..627	CDD:188660	47/124 (38%)
Rgs18	NP_075019.1	RGS	87..199	CDD:295367	42/116 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810