Protein Alignment RSG7 and RGS3

DIOPT Version :10

• Sequence 1: NP_523380.2
• Gene: RSG7 / 32674
• FlyBaseID: FBgn0024941
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_652759.4
• Gene: RGS3 / 5998
• HGNCID: 9999
• Length: 1094
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 78/256 - (30%)
• Similarity: 125/256 - (48%)
• Gaps: 44/256 - (17%)

  Fly   390 WDVHRPMPGCVNTTEIDIKKAYRRGGSSHG-----TG---SAGASLAKNPVEQLTRIIALRKQKL 446
            |.:  |.|..:.      |:..|.|||.|.     ||   .:||....:..|      |.||
Human   870 WGM--PSPSTLK------KELGRNGGSMHHLSLFFTGHRKMSGADTVGDDDE------ASRK--- 917

  Fly   447 ERRTIKVSKAAEALVAYYDQYNEFDYFITSPELPNPWQTDSTEMWDTEKNSKEVPVRRVKRWAFS 511
             |::..::|..:..:..:.:.||      ||..|...:.|  :|..:.|.:.|    ...:|..|
Human   918 -RKSKNLAKDMKNKLGIFRRRNE------SPGAPPAGKAD--KMMKSFKPTSE----EALKWGES 969

  Fly   512 LRELLNDAIGREQFTKFLEKEYSGENLKFWESVQEMKAL-PQSEIKEAIQKIWQEFLAPEAPCPV 575
            |.:||....|...|..||..|:|.|||:||.:.::.|.: .||::....:||:.|::|.:|...|
Human   970 LEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEV 1034

  Fly   576 NVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLNCSRKKI 636
            |:||.:.|..::.:.|.:   |.|||:|...::.||:.|||.|:||||:|.|.:|  :||:
Human  1035 NLDSYTREHTKDNLQSVT---RGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLIN--QKKM 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_523380.2	DEP_RGS7-like	222..309	CDD:239897
		RGS_DHEX	306..407	CDD:375589	3/16 (19%)
		GGL	432..493	CDD:128520	13/60 (22%)
		RGS_R7-like	504..627	CDD:188660	46/123 (37%)
RGS3	NP_652759.4	C2_RGS-like	35..154	CDD:176067
		PDZ_RGS3-like	194..270	CDD:467195
		PHA03247	<586..748	CDD:223021
		RGS_RGS3	970..1083	CDD:188668	44/115 (38%)