Protein Alignment RSG7 and Rgs12

DIOPT Version :10

• Sequence 1: NP_523380.2
• Gene: RSG7 / 32674
• FlyBaseID: FBgn0024941
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_006251413.1
• Gene: Rgs12 / 54292
• RGDID: 3564
• Length: 1457
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 123/545 - (22%)
• Similarity: 213/545 - (39%)
• Gaps: 146/545 - (26%)

  Fly   168 HHHAHPQQSAAGQSAAQPPQPPTATALAVPSASHHQRGGKNEDAPNI----LVYKKMEAIIEKMQ 228
            ||..| |..|.....|....|.|:..|..|::|          .|.:    ::|:.|..:||.::
  Rat   347 HHKIH-QGIARRFGFACTADPDTSGCLEFPASS----------LPVLQFISVLYRDMGELIEGVR 400

  Fly   229 AESTGVAVRTVKAFMS------KVPSVFTGADLVAWILKNFDVEDVTEALHFAHL---LSSHGY- 283
            |          :||:.      :..|..:.:|..   :.||:.|:.:..:....|   .|.||.
  Rat   401 A----------RAFLDGDADAHQNNSTSSNSDSG---IGNFNQEEKSNRVLVVDLGGGSSRHGQG 452

  Fly   284 ----------------------IFPIDDHA---------------LTVKNDGTFYRFQTPYFWP- 310
                                  .|..|..|               || |:.|..:..:.|   |
  Rat   453 SSPGWESVSGRGSQPWSAPWNGTFCHDSEAGSPLETSPNTDRFWDLT-KHSGPVFHMEVP---PA 513

  Fly   311 ---------------SNC-----WEPENTDYAVYLCKRTMQNKTRLELAD-YEAENLAKLQKMFS 354
                           |:|     |.|.:. ...:.|......::..:..| :.:.|...|....|
  Rat   514 TLRSSIPPSKRGATGSSCGFNQRWLPVHV-LQEWQCGHASDQESYTDSTDGWSSVNCGTLPPPMS 577

  Fly   355 R------KWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWDVHRPMPGCVNTTEIDIKKAYRR 413
            :      :.|..|.||...:   :||| ..||....|.  .:..||.    |..|:.| ||:.:.
  Rat   578 KIPADRYRVEGSFAQAPLST---QKRD-WSRKAFGMQN--LFGPHRN----VRKTKED-KKSSKL 631

  Fly   414 GGSSHGTGSAGASLAKNPVEQLTRIIALRKQKLERRTIKVSKAAEALVAYYDQYNEFDYFITSPE 478
            |        .|.:||     |.::..:.|:.....|...::::.:.|    :.....|..:|..:
  Rat   632 G--------RGVALA-----QTSQRTSARRSFGRSRRFSLTRSLDDL----ESATVSDGELTGAD 679

  Fly   479 LPNPWQTD---STEMWDTEKNSKEVPVRRVKRWAFSLRELLNDAIGREQFTKFLEKEYSGENLKF 540
            |.:....:   |.....:.::.:.:..|||..||.|...||.|.:|...|:.||.||:|.||:.|
  Rat   680 LKDCISNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILF 744

  Fly   541 WESVQEMKALPQSEIKE---AIQKIWQEFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCFDV 602
            |::.:....:|..:.||   ..::|:.:||..:|..|||:||:: :||.:.:|:|. |:  .|..
  Rat   745 WQACECFSHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQA-QLADDILNAPH-PD--MFKE 805

  Fly   603 AASHVYHLMKSDSYSRYLRSDMYKD 627
            ....:::|||.|||:|:|:|.:|::
  Rat   806 QQLQIFNLMKFDSYTRFLKSQLYQE 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_523380.2	DEP_RGS7-like	222..309	CDD:239897	22/133 (17%)
		RGS_DHEX	306..407	CDD:375589	25/128 (20%)
		GGL	432..493	CDD:128520	8/63 (13%)
		RGS_R7-like	504..627	CDD:188660	47/125 (38%)
Rgs12	XP_006251413.1	PDZ_RGS12-like	20..95	CDD:467194
		PTB_RGS12	227..358	CDD:269984	5/11 (45%)
		RGS_RGS12	716..830	CDD:188696	42/117 (36%)
		RGS12_us1	836..953	CDD:465199
		RBD1_RGS12	962..1031	CDD:340656
		Ubl1_cv_Nsp3_N-like	1032..1104	CDD:475130
		RGS12_us2	1106..1180	CDD:435461
		GoLoco	1188..1209	CDD:214645
		RGS12_usC	1238..1387	CDD:465198