DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RSG7 and Rgs11

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_062211.1	Gene:	Rgs11 / 54291	RGDID:	3563	Length:	467	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	158/454 - (34%)
Similarity:	241/454 - (53%)	Gaps:	36/454 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 RGGKNEDAPNILVYKKMEAIIEKMQAESTGVAVRTVKAFMSKVPSVFTGADLVAWILKNFDVEDV 268
            ||......|::   .|||.::..||....||.:|:.:..::.:|....|.|:|.|:::.|.:.:
  Rat    11 RGCSRMQRPHL---SKMERVVVSMQDPDQGVKMRSQRLLITVIPHAVAGRDIVEWLVQKFCISE- 71

  Fly   269 TEALHFAHLLSSHGYIFPI-DDHALTVKNDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQN 332
            .||||...||:.||||:|: :...||::.|.|.|||||||||.|..|.....|||:||.|:.:|.
  Rat    72 EEALHLGTLLTQHGYIYPLRESRDLTLRPDETPYRFQTPYFWTSTLWPAAELDYAIYLAKKNIQK 136

  Fly   333 KTRLELADYEAENLAKLQKMFSRKWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWDVHRPMP 397
            :.  .|.|||.|:...|.|..:..|:.:.|||..|.:.||:|.|.:|.|:..||:.:|.|::|.|
  Rat   137 QG--ALVDYEKEHYTLLHKKINHAWDLVLMQAREQLRAAKQRRKGDRLVISCQEQTYWLVNKPPP 199

  Fly   398 GCVNTTEIDIKKAYRRGGSSHGTGSAGASLAKNPVEQLTRIIALRKQKLERRTIKVSKAAEALVA 462
            |..|..|    :...||..:.......:...|..:|      ..|| .|.|..:|.|...||.:.
  Rat   200 GAPNVLE----QGPERGSDNPSQVQMSSDFYKCEIE------CFRK-ALSRNRVKSSVCLEAYLK 253

  Fly   463 YYDQYNEFDYFITSPELPNPWQTDSTEMWDTEKNSKEVPVR-RVKRWAFSLRELLNDAIGREQFT 526
            :..|:...|..::.....|||.||....|.....:...|.: ||:||:||.||||:|.:||..|.
  Rat   254 FSSQHGPHDPILSGCLPSNPWITDDVTYWVMNAPNVAAPTKLRVERWSFSFRELLDDPVGRIHFM 318

  Fly   527 KFLEKEYSGENLKFWESVQEMKALPQSEIKEAIQKIWQEFLAPEAPCPVNVDSKSVELAREAVNS 591
            .||:||:|.|||.|||:.:|::...|:::...:..::|:||||.|...:|:||:::|...|.:..
  Rat   319 DFLQKEFSAENLSFWEACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMEWTLEGLRQ 383

  Fly   592 PSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLNCS--------------RKKIKSIPN 641
               |:|:..|.|..|:|.|||.|||.|:|:||:|:..|..:              ||.:.|.|:
  Rat   384 ---PHRYVLDAAQLHIYMLMKKDSYPRFLKSDIYRGLLEEAVIPLETKRWPFPFLRKPLHSSPS 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897	33/87 (38%)
		GGL	432..493	CDD:128520	17/60 (28%)
		RGS_R7-like	504..627	CDD:188660	55/122 (45%)
Rgs11	NP_062211.1	DEP_RGS7-like	26..113	CDD:239897	33/87 (38%)
		GGL	224..284	CDD:128520	18/66 (27%)
		RGS	295..420	CDD:295367	56/127 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101587
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810