DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RSG7 and RGS21

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_001034241.1	Gene:	RGS21 / 431704	HGNCID:	26839	Length:	152	Species:	Homo sapiens

Alignment Length:	142	Identity:	42/142 - (29%)
Similarity:	76/142 - (53%)	Gaps:	9/142 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 PVRRVKRWAFSLRELLNDAIGREQFTKFLEKEYSGENLKFWESVQEMKALPQSE-IKEAIQKIWQ 564
            |......|:.::..||.:..|.:.|..||:.|:|.||::||.:.::.|....:: |....:.|:.
Human    11 PTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYS 75

  Fly   565 EFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDYL 629
            ||:..:||..:|:|..:.:|..:.:   :.|...|||.|...:|.||..||:.|:|:|::||..:
Human    76 EFIEADAPKEINIDFGTRDLISKNI---AEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLV 137

  Fly   630 NCSRKKIKSIPN 641
            |.     :.:||
Human   138 NS-----QQVPN 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897
		GGL	432..493	CDD:128520
		RGS_R7-like	504..627	CDD:188660	37/123 (30%)
RGS21	NP_001034241.1	RGS_RGS21	25..135	CDD:188678	36/112 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810