DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RSG7 and rgs14a

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	XP_009305919.2	Gene:	rgs14a / 327368	ZFINID:	ZDB-GENE-030131-5579	Length:	554	Species:	Danio rerio

Alignment Length:	143	Identity:	48/143 - (33%)
Similarity:	76/143 - (53%)	Gaps:	10/143 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 PVRRVKRWAFSLRELLNDAIGREQFTKFLEKEYSGENLKFWESVQEMKALPQS---EIKEAIQKI 562
            |..||..||.....||.|.:|...||:||..|.|.||:.|:::.::.|.:|.|   |:|:..:.|
Zfish    98 PASRVVSWAVCFEHLLEDHVGVRYFTEFLRSEVSAENILFYQACEKFKKIPTSRLEEMKKEARLI 162

  Fly   563 WQEFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKD 627
            :..||:..:...||:|..:....||.    ..|....|:.|.:.::.|||.|||:|::||.:|:
Zfish   163 YDTFLSESSLHAVNIDDTAQTEEREL----EMPTPDMFNKAQAQIFKLMKMDSYTRFVRSPLYQ- 222

  Fly   628 YLNCSRKKIKSIP 640
              ||....::|.|
Zfish   223 --NCMLACVESRP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897
		GGL	432..493	CDD:128520
		RGS_R7-like	504..627	CDD:188660	43/125 (34%)
rgs14a	XP_009305919.2	RGS_R12-like	109..223	CDD:188661	39/120 (33%)
		RGS12_RBD	343..415	CDD:176412
		TGS	423..483	CDD:330245
		GoLoco	508..529	CDD:308026
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810