Protein Alignment RSG7 and rgs-7

DIOPT Version :10

• Sequence 1: NP_523380.2
• Gene: RSG7 / 32674
• FlyBaseID: FBgn0024941
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001360776.1
• Gene: rgs-7 / 180645
• WormBaseID: WBGene00004350
• Length: 824
• Species: Caenorhabditis elegans
• Alignment Length: 730
• Identity: 147/730 - (20%)
• Similarity: 230/730 - (31%)
• Gaps: 250/730 - (34%)

  Fly    75 NGTGSSVSPAATGTGAVATAASAPAAAGTTSASPPAS----------------NPTTASTSTASV 123
            :.|.||.|.|...:...|.....|....||::..|.|                :|..:||..:..
 Worm   151 SSTYSSSSEAHRLSSLRAQTEWKPQLTSTTTSFQPLSPMNHHDKENGPFKAPMSPVCSSTPRSQR 215

  Fly   124 VGAKTAAATTTSSSSATSSSTAAAGSKQSGSSGGLLTVSGNHHHHHHAHPQQSAAGQSAAQPPQ- 187
            :..|.........||...|.:....|....|...:...|...|::.:.||.|    ...|:|.|
 Worm   216 MYRKNPKYRRQFGSSLQLSESRLEESTSQESERAVTPESWMEHNNENEHPDQ----MMFAKPKQG 276

  Fly   188 ---PPTATALAVPSASHHQRGGKNEDAPNILVYKKMEAIIEKMQAESTGVAVRTVKAFMSKVPSV 249
               .|.|..|....|.|                |.:..||                 |:|   ..
 Worm   277 SFPRPEAFGLDNAYAKH----------------KDIRGII-----------------FLS---MS 305

  Fly   250 FTGADLVAWILKNFDVEDVTEALHF---AHLLSSHGYIFPIDDHALTVKNDGTFYRFQTPYFWPS 311
            ..|..|..         :|..|.:|   |...|...|:..:..|..:.::..:..:::..   |.
 Worm   306 LCGRRLTL---------NVQNAAYFCSAARPTSVCSYVSAVLCHRPSSQSSSSSRQYRQR---PD 358

  Fly   312 NCWEPE--------NTDYAVYL-----CKRTMQNKTRLELADYEAEN----------LAKLQKMF 353
            .|:...        :.|.:.|.     |.|.:...|..|:....||.          ::::.|..
 Worm   359 ECYRTRLVTNCNSPSFDESFYFTFSENCVRDLLIVTVYEMDSNNAEKKRILGCMTFPVSRILKKA 423

  Fly   354 SR--------------------KWEFIFMQAESQSKVAKKRDKLERKVLDSQERAFWD------- 391
            |:                    ..|..|:..:.|   .:|::..:||:|..:.:.|::
 Worm   424 SQVVGDPFPHYRRQDPMEDVEINNEGFFLLNKDQ---GRKQNFPQRKMLQVRRQTFYEDPAFTGV 485

  Fly   392 ---------------VHRPMPGCVNTTEIDIKKAYRRGGSSHGTG----------SAGASL---A 428
                           :....|......|:.:...||..|||...|          ||.:|.   |
 Worm   486 SSAGSSVISNNTGGQMTMASPRLSVPNELTMGDYYRSTGSSDMRGRSTNNLLDYTSASSSTNGSA 550

  Fly   429 KNPVEQLTRIIALRKQKLERRTIKVSKAAEALVAYYDQYNEFDYFITSPE--------------- 478
            ..|          .|.||.|.|:      .::.....:.|..|....|||
 Worm   551 GGP----------EKLKLHRATL------PSITTTTSENNSDDAKSLSPEQSPTDHHFLCPDDNG 599

  Fly   479 --------------------------------LPNPWQTDSTEMWDTEKNSKEVPVRR------- 504
                                            ..|..|.:..|. |.||.....|:.|
 Worm   600 GVYGAGPAHSAIKKSSVRRAASFTFSPKHSSSKTNLRQLNGREE-DKEKKRFLGPISRTLSYLRS 663

  Fly   505 -----------------VKRWAFSLRELLNDAIGREQFTKFLEKEYSGENLKFW---ESVQEMKA 549
                             |::|..|...|||:..|...|.:||:||:|.||:.||   |..::||.
 Worm   664 KMDLALSTSSLYPSRDDVRQWEISFESLLNNKFGCALFRQFLKKEFSDENMDFWLECEEFKKMKD 728

  Fly   550 LPQSEIKEAIQKIWQEFLAPEAPCPVNVDSKSVELAREAVNSPSGPNRWCFDVAASHVYHLMKSD 614
            ..:|..::||: |:.||:|..:|..||:||.:....:.||.:...|:  .|.:|.|.|..||..|
 Worm   729 GKKSTTQKAIE-IYSEFVAEHSPKEVNLDSDTRAATKAAVEAGCKPD--TFALAQSRVEQLMSKD 790

  Fly   615 SYSRYLRSDMYKDYL 629
            ||.|:||..::.|.|
 Worm   791 SYRRFLRDRLFLDLL 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_523380.2	DEP_RGS7-like	222..309	CDD:239897	13/89 (15%)
		RGS_DHEX	306..407	CDD:375589	22/165 (13%)
		GGL	432..493	CDD:128520	13/107 (12%)
		RGS_R7-like	504..627	CDD:188660	48/149 (32%)
rgs-7	NP_001360776.1	C2	310..427	CDD:214577	20/128 (16%)
		RGS	687..792	CDD:459870	40/107 (37%)