DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RSG7 and rgs-3

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_495223.1	Gene:	rgs-3 / 174020	WormBaseID:	WBGene00004346	Length:	363	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	73/310 - (23%)
Similarity:	121/310 - (39%)	Gaps:	79/310 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 VLDSQERAFWDVHRPMPGCVNTTEIDIKKAYRRGGSSHGTGSAGASLAKNPVEQLTRIIALRK-- 443
            :.|.:|:    |:|..|....|..::..:|     :|...|:....|..:..:||.|:...:.
Worm    80 MFDGKEK----VNREQPPMPTTDGVEYPRA-----ASWAAGNCANVLNDDKGKQLFRVFLFQSLA 135

  Fly   444 ----------QKLERRTI---KVSKAAEALVAYYDQYNEFDYFITSPELPNPWQTDSTEMWDTEK 495
                      :||::..|   ||:.|.|.|..|....|     ::|..:.:.....::|..|.|:
Worm   136 EENLAFLEAMEKLKKMKISDEKVAYAKEILETYQGSIN-----LSSSSMKSLRNAVASETLDMEE 195

  Fly   496 NS---KEV--------------------------PVRRVKRWAFSLRELLNDAIGREQFTKFLEK 531
            .:   |||                          |....::||.|...||.:.:||..|..||..
Worm   196 FAPAIKEVRRLLENDQFPRFRRSELYLEYLEELLPRSYAEKWAQSFEGLLGNHVGRHHFRIFLRS 260

  Fly   532 EYSGENLKFWESVQEM-----KALPQSEIKEAIQKIW-QEFLAPEAPCPVNVDSKSVELAREAVN 590
            .::.|||:|||:|.|.     ||...:.:.:.|...: .|....|...|..|        |:.:.
Worm   261 IHAEENLRFWEAVVEFRSSRHKANAMNNLGKVILSTYLAEGTTNEVFLPFGV--------RQVIE 317

  Fly   591 SPSGPNR---WCFDVAASHVYHLMKSDSYSRYLRSDMYKDYLNCSRKKIK 637
            .....|:   ..||.|..||..::::|.|.|:|:|..|.|.|:    |:|
Worm   318 RRIQDNQIDITLFDEAIKHVEQVLRNDPYVRFLQSSQYIDLLS----KLK 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897
		GGL	432..493	CDD:128520	15/75 (20%)
		RGS_R7-like	504..627	CDD:188660	38/131 (29%)
rgs-3	NP_495223.1	RGS	112..218	CDD:214613	21/110 (19%)
rgs-3	NP_495223.1	RGS	240..358	CDD:279009	36/125 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910