DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RSG7 and axin2

DIOPT Version :9

Sequence 1:	NP_001245722.1	Gene:	RSG7 / 32674	FlyBaseID:	FBgn0024941	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	XP_002935041.1	Gene:	axin2 / 100380149	XenbaseID:	XB-GENE-6449828	Length:	707	Species:	Xenopus tropicalis

Alignment Length:	174	Identity:	43/174 - (24%)
Similarity:	75/174 - (43%)	Gaps:	23/174 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   475 TSPELPNPWQTDSTEMWDTEK--------NSKEVPVR----------RVKRWAFSLRELLNDAIG 521
            ||...|.|.|  .|:.:.:||        ..||..:|          |..||..||..||:|..|
Frog    20 TSLRPPVPGQ--ETKNYKSEKFTMDSQHLRHKEDYIREAEGCVANDSRFSRWGRSLNLLLDDQDG 82

  Fly   522 REQFTKFLEKEYSGENLKFWESVQEMKALPQSEIK--EAIQKIWQEFLAPEAPCPVNVDSKSVEL 584
            ...|..:||.|...:.|.||.:....:|:...|.|  :..:.|::.::...:.....:...:...
Frog    83 ATLFRMYLEGEGLVDLLSFWFACNGFRAMDPLEPKTSKTAKAIYRWYVQNSSAVSCRLKPSTRTQ 147

  Fly   585 AREAVNSPSGPNRWCFDVAASHVYHLMKSDSYSRYLRSDMYKDY 628
            .:|.|.:.. .|:..||.|...:...|:.::::.:|:||:.|:|
Frog   148 VKECVKNQQ-LNKTVFDQAQQEIQRAMEQEAFTSFLQSDICKEY 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RSG7	NP_001245722.1	DEP_RGS7-like	222..309	CDD:239897
		GGL	432..493	CDD:128520	6/17 (35%)
		RGS_R7-like	504..627	CDD:188660	30/124 (24%)
axin2	XP_002935041.1	RGS_Axin	73..189	CDD:188662	26/116 (22%)
		Axin_b-cat_bind	383..426	CDD:370146
		DIX	630..702	CDD:366298
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910