DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4829 and si:dkey-222h21.12

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_021333865.1	Gene:	si:dkey-222h21.12 / 795959	ZFINID:	ZDB-GENE-090312-33	Length:	605	Species:	Danio rerio

Alignment Length:	613	Identity:	205/613 - (33%)
Similarity:	317/613 - (51%)	Gaps:	71/613 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 LNLGITSTAT-TPSDDVLPNVAASTAATTAAPPTWLADQIKIDTSEQYNSILGVYQHGAVSSDNL 297
            |.|.:|..:| |.:...||:|..:|...|                    .|:...:..||::|..
Zfish     3 LFLTLTQRSTVTHTRRSLPSVKLNTPIMT--------------------PIVNCNEKAAVAADAE 47

  Fly   298 ECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERHATAIDAREVAPYE 362
            .|||||..||.:||||||||||||||..::..||||||||.:..:||........|:|||.||..
Zfish    48 ICSKIGRDILGRNGSAVDAAIAALLCVSVINPQSMGIGGGSVFTIYNAINGTVEIINARETAPMS 112

  Fly   363 ATEDMFAQQPENSDKGPLSIAVPGEVMGYHVAHQKFGQLPWAELVAPSLELCEKGYHVSQHMERA 427
            ||.:||....:..:.| |.||||||:.||.:||.::|:|||.:|..||::|..:|:::|:.:..|
Zfish   113 ATANMFDNNTQKENPG-LLIAVPGELRGYKMAHDRYGKLPWKDLFEPSIKLASEGFNISKGLAYA 176

  Fly   428 LDIALPYIKEHEQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLLAENGPMDMYNGTIAKLLAED 492
            :::....|:::...:........||.......:.|| |.|||:.:||.||...|:|::.:.:.::
Zfish   177 INMEERKIRKNIALREVFCDSDNKPLKESNFTRFPK-LAKTYRTIAEEGPDAFYDGSLTQSILDE 240

  Fly   493 LQDMGSIILADDLESYEAD-------------VINSITMDLGDDTLYVVPPV-----SSGSVVAH 539
            :...|..|..:||:.|:.|             :..:.|...|...|.::..:     ::||..:|
Zfish   241 ITVAGGNITREDLKRYKPDLQKYALNFTVGKYIFFAPTAPFGGPVLALIMKILLGNGTAGSSKSH 305

  Fly   540 VLAILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGD-MHFIDARELVSRLNSPDFGD 603
            :|....|:|.:.:.:||.|....|.||..||.:||.||:.:|.| :|..:..|.|..:.|..|.|
Zfish   306 LLHYYSGFNLSNKSVSTPENMTLTYHRIIEAFRFANAQKAKLADPLHEKNVTEFVKYMTSDSFAD 370

  Fly   604 QNRAKINDSHVLPDAQAYGANFAAIEDLDGTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRTGI 668
            ..|.||.|..........|...  :.|..|||:|.|:|.:|.||:||||||::||||::....||
Zfish   371 NIRNKIKDDIKQTSYDEQGIKI--VPDDHGTSHLSVIAKDGSAVAVTSSINNFFGSGVMSCLRGI 433

  Fly   669 VLNNGMNDFA---VKNNIFALPQSQSNKIEAHKRAMSSQSPILLADKDG-NMKMVIGAAGGSKII 729
            :.|:.|:|:.   :||.        .|.|:..||.:||..|.::.|||. .::||.|.|||:.|.
Zfish   434 IFNDQMSDYTSPEMKNG--------PNAIKPGKRPLSSMCPTIILDKDSRKVRMVAGGAGGTNIT 490

  Fly   730 PAVVEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHKLK------- 787
            .:|.:|..:.|:|..:|::||..||.  |:.|:|...|| ||..:::..|:::.|.:.
Zfish   491 TSVAQVILDHLYFDYNLQKAVAEPRV--QVPPNVTNVEE-GFDSTVMGWLSRKYHNISQYTSLTM 552

  Fly   788 -SISVKTGSVVTAISRNATAIYANADYR 814
             .:..|.||.|.|:|....|:|    ||
Zfish   553 VQVVEKEGSQVCAVSDTRDAVY----YR 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	186/540 (34%)
si:dkey-222h21.12	XP_021333865.1	G_glu_transpept	55..570	CDD:307247	182/529 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.790