DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4829 and CG17636

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_001245442.1	Gene:	CG17636 / 5740847	FlyBaseID:	FBgn0025837	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	187/541 - (34%)
Similarity:	299/541 - (55%)	Gaps:	33/541 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 GAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERHATAID 354
            |||:|:.:.|:::|..||...|||.|||||.:||.|::...|:|:|||.:..:|:|:...:..:.
  Fly    54 GAVASNGVGCAEVGGSILDIGGSAADAAIATMLCEGVMLPHSLGVGGGFVATIYSRETEFSEVLI 118

  Fly   355 AREVAPYEATEDMFAQQPENSDKGPLSIAVPGEVMGYHVAHQKFGQLPWAELVAPSLELCEKGYH 419
            |||.||..||:|||.   :....|.||.|||.|:.||...|.|:|:|||..|..|:::||.:|..
  Fly   119 ARETAPAAATQDMFV---KTEITGALSCAVPAEIYGYSELHDKYGRLPWKTLFQPTIDLCRRGIL 180

  Fly   420 VSQHMERALDIALPYIK-EHEQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLLAENGPMDMY-N 482
            ||:::...|......|: |....:|::|.:|.:.:..|.|:. ...|.:|.:::|:.|...:| .
  Fly   181 VSRYLSGVLQREEERIRNEPSMAEIFINPKTDEVYKQGEVMY-RHTLAETLEIIADEGAKAIYGG 244

  Fly   483 GTIAKLLAEDLQDMGSIILADDLESYEADVINSITMDL-------GDDTLYVVPPVSSGSVVAHV 540
            |.:.:.|.||:|.||.|:..:||:||      ::..::       |...|......:||:|:..:
  Fly   245 GRVGRKLVEDIQAMGGIVTEEDLQSY------NVRWEMPLHSHFSGGYKLITSTLPTSGAVLTFM 303

  Fly   541 LAILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGDMHF-IDARELVSRLNSPDFGDQ 604
            |.:::.. :|:   :|::...|.|    |..|.|:..|..|||:|: .|.:|:...|..|.|..:
  Fly   304 LNVMEPL-YTS---NTDKYWQRLI----ETFKHAYGHRTNLGDIHYEPDVQEMYENLIDPAFAAE 360

  Fly   605 NRAKINDSHVLPDAQAYGANFAAIEDLDGTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRTGIV 669
            .|..|.|.....|...||||||..|| .||:::.||||||||:||||:|||:.|:.:...:||.:
  Fly   361 IRKLILDDRTFEDMSYYGANFANEED-HGTAHISVLAPNGDAISVTSTINSHLGAKVRSRQTGFI 424

  Fly   670 LNNGMNDFAV--KNNIFALPQSQSNKIEAHKRAMSSQSPILLADKDGNMKMVIGAAGGSKIIPAV 732
            ||:.|:||:.  |.|.:.:|.|.:|.|:..||.|||..|.::.|..||:|:::|.||||||..:|
  Fly   425 LNDEMDDFSTPGKINAYGIPASPANFIKPGKRPMSSTCPSIVLDTHGNVKLIVGGAGGSKITTSV 489

  Fly   733 VEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHKLKSI-SVKTGSV 796
            .:.........:.:.:||::.|.:|||.|..::.|.: .....:..|:..||.::.: ..|..|.
  Fly   490 AQTILRYFVLHEPIEKAVNSGRLHHQLAPMHIDMEPN-VPRHTVAYLSAIGHDIRFLEDDKAYSA 553

  Fly   797 VTAISRNATAIYANADYRKRG 817
            .|||....|..:...|.|:.|
  Fly   554 QTAIGILGTEPHPVCDRRRVG 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	180/523 (34%)
CG17636	NP_001245442.1	G_glu_transpept	69..574	CDD:279371	180/524 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447725
Domainoid	1	1.000	227	1.000	Domainoid score	I423
eggNOG	1	0.900	-	-		E1_COG0405
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I741
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		otm51323
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	P	PTHR11686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R489
SonicParanoid	1	1.000	-	-		X210
	12	11.830