DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4829 and ggt5a

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_005167440.1	Gene:	ggt5a / 569734	ZFINID:	ZDB-GENE-080226-1	Length:	556	Species:	Danio rerio

Alignment Length:	540	Identity:	196/540 - (36%)
Similarity:	294/540 - (54%)	Gaps:	23/540 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 GVYQHGAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERH 349
            |:|:..||::|:..|||:|..|||..|||||.|||.|||..::..||||||||.:..:.....|
Zfish    38 GLYKKAAVAADSETCSKVGRDILQSGGSAVDGAIATLLCTSVINPQSMGIGGGSIFTIREPNGR- 101

  Fly   350 ATAIDAREVAPYEATEDMFAQQPENSD--KGPLSIAVPGEVMGYHVAHQKFGQLPWAELVAPSLE 412
            ...|:|||..|.....|:.|..|....  :|...|.|||::.||..||:.:|:||||.|..|::.
Zfish   102 VRIINAREAIPKNFKTDLLATCPTTIQPMEGAHWIGVPGDIRGYERAHRLYGRLPWACLFQPTIN 166

  Fly   413 LCEKGYHVSQHMERALDIALPYIKEHEQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLLAENGP 477
            :..:|..:...:.|.|.:.|....|....|::.| |.|:....|.:||..| |..|.:::|::|.
Zfish   167 MAREGIRIPYMLSRFLPLVLKEKPESPLRQLFQN-EKGELLKEGDIVKFNK-LADTLEIIAKHGA 229

  Fly   478 MDMYNGTIAKLLAEDLQDMGSIILADDLESYEADVINSITMDLGDDTLYVVPPVSSGSVVAHVLA 542
            ..:|.|.|||.|..|:|..|..:..:||.|:.|...::..::|||..:|..||.:.|::::.||.
Zfish   230 DALYTGDIAKDLVSDIQAAGGTVSLEDLNSFRASESDAWEVNLGDYDMYFPPPPAGGAILSFVLN 294

  Fly   543 ILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGDMHFIDARELVSRLNSPDFGDQNRA 607
            .:.|:|.::..|..:| |..|..|:.|..|||...:..:.|.:|....|.|..:.. .|.|:.||
Zfish   295 TMLGFNLSSASLEGDE-KVLTFQRYVETCKFANGLKKFMKDPNFASQTEAVEIIQK-HFADKVRA 357

  Fly   608 KINDSHVLPDAQAYGANFAAIEDLDGTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRTGIVLNN 672
            ||:..|.. ||..|  |.....|..||:::.|||.:|.||||||:||..|||.:...:|||:|||
Zfish   358 KISPDHSY-DASYY--NVTPYLDSHGTTHVSVLAEDGMAVSVTSTINHIFGSRIFSSKTGILLNN 419

  Fly   673 GMNDFAVKNNIFALPQSQSNKIEAHKRAMSSQSPILLADKDGNMKMVIGAAGGSKIIPAVVEVAA 737
            .:.||..|          :::|.|.::..||.||::|..:.....:||||:|||.|...|.....
Zfish   420 ELADFCGK----------TDQIHAGEQPPSSMSPVVLHSRSKKHIVVIGASGGSMITTGVALTLM 474

  Fly   738 NVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHKLKSISVKTGSVVTAISR 802
            |.|||||.|:.::|||..:.. ..:||.: |..|.:.:::.|.|.|||:|...: ..:||.|:|:
Zfish   475 NFLWFGKTLQDSIDAPVVFVD-SKNVLNF-EPSFDKIVVESLNKIGHKVKVPQI-FYNVVNAVSK 536

  Fly   803 NATAIYANADYRKRGGVAGF 822
            ....|.|.:|.||:|..||:
Zfish   537 ENQCIVAVSDSRKKGKAAGY 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	184/512 (36%)
ggt5a	XP_005167440.1	G_glu_transpept	58..551	CDD:279371	184/513 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579870
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810