DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4829 and ggt1l2.2

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	XP_009294029.1	Gene:	ggt1l2.2 / 566746	ZFINID:	ZDB-GENE-090312-37	Length:	566	Species:	Danio rerio

Alignment Length:	555	Identity:	200/555 - (36%)
Similarity:	320/555 - (57%)	Gaps:	44/555 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 YQHGAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERHAT 351
            |.:.||::|..:||:||..|||:||||||||||||||..|:..||||||||.:..:||.......
Zfish    37 YDNAAVAADARKCSEIGRDILQRNGSAVDAAIAALLCVSLVNAQSMGIGGGLVFTIYNAPSGKVE 101

  Fly   352 AIDAREVAPYEATEDMFAQQPENSDKGPLSIAVPGEVMGYHVAHQKFGQLPWAELVAPSLELCEK 416
            .|::||.||..|:|:||...||.:..| |.||||||:.||.:||::.|:|||.||..||::|..:
Zfish   102 TINSRETAPMSASENMFGTNPEKAKPG-LFIAVPGELRGYALAHKRHGKLPWKELFQPSIKLASE 165

  Fly   417 GYHVSQHMERALDIALPYIKEH--------EQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLLA 473
            |:.:.:.:..|::.....|:.:        :...|.|.        ....::.|| |.:||:.::
Zfish   166 GFKIGKALANAINETRATIQRNATLCEVFCDSNNIVLK--------ENDTIRFPK-LAETYRKIS 221

  Fly   474 ENGPMDMYNGTIAKLLAEDLQDMGSIILADDLESYEADVI--NSITMDLGDDTLYVVPPVSSGSV 536
            |.||...|||::.:.:.:|::..|.||..:||::| ..|:  :::...:|....:.......|.|
Zfish   222 EEGPDAFYNGSLTQSIVDDIKAAGGIITREDLKAY-GPVLTEHALNFTVGKYIFHAPGAPFGGPV 285

  Fly   537 VAHVLAILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGDMHFIDARELVSRLNSPDF 601
            :|.:|.:::|||.:.:.::|...|..|.||..||.:||..|:.:|||..|.:..|.|..:.|..|
Zfish   286 LALILKVMKGYNISWKSMATTGNKTLTYHRLIEAFRFADVQKSKLGDPLFENITEHVKNMVSDSF 350

  Fly   602 GDQNRAKINDSHVLPDAQAYGANFAAIEDLD------GTSNLVVLAPNGDAVSVTSSINSYFGSG 660
            .|..|:||.|     |.:.  .::...||::      |||::.|||.:|.||:||||||:|||||
Zfish   351 ADHIRSKIKD-----DLKQ--TSYDEQEDINTVPEDHGTSHVSVLAKDGSAVAVTSSINNYFGSG 408

  Fly   661 LIGPRTGIVLNNGMNDFAVKNNIFALPQSQSNKIEAHKRAMSSQSPILLADKD---GNMKMVIGA 722
            ::...|||:.|:.|.|| ::..:.:.| :::|||:..||.:||..|.::.:||   ..::||:|.
Zfish   409 VMSRSTGIIFNDQMWDF-IEPELMSGP-NKNNKIKPGKRPLSSMCPTIIFEKDDRKNKVRMVVGG 471

  Fly   723 AGGSKIIPAVVEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHKLK 787
            |||:.|..:|.:|..|.|:||.||:::|:..|.  |:..:|...|:| |.:::::.|.::.|.:
Zfish   472 AGGTNITTSVAQVILNHLFFGFDLQKSVNTSRV--QITLNVTNVEKD-FDKAVIEGLKQKNHHI- 532

  Fly   788 SISVKTGSVVTAISRNATAIYANADYRKRGGVAGF 822
             :.....|||.||.|....:.|.:|.|..|..||:
Zfish   533 -LHDTALSVVQAIGRKGKKVCAQSDTRNDGHAAGY 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	189/529 (36%)
ggt1l2.2	XP_009294029.1	G_glu_transpept	55..561	CDD:279371	189/530 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D176986at33208
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.790