DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4829 and CG1492

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	221/550 - (40%)
Similarity:	328/550 - (59%)	Gaps:	16/550 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 NSILGVYQHGAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNR 345
            ||.|..:...|:.||:..||::...:|:..|||||.|:|||:||||:.:||||||||.:||||..
  Fly    51 NSPLHRFSRAAICSDSDVCSQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVA 115

  Fly   346 KERHATAIDAREVAPYEATEDMFAQQPENSD--KGPLSIAVPGEVMGYHVAHQKFGQLPWAELVA 408
            ||..:.:|.|||:||.....|.|:...:..|  :...|||||.|:.||.||||:||:|.|.:||.
  Fly   116 KENKSYSILAREMAPLALRADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVL 180

  Fly   409 PSLELCEKGYHVSQHMERALDIALPYIK-EHEQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLL 472
            |:||||.:||.:.:|...||.:....|: :....:::::.:||:....|.:::|...||.||..|
  Fly   181 PTLELCRRGYRLYKHQYDALILNQDMIRADSGLRRMFIDPDTGRFWPLGHLIRPAAQLCNTYDRL 245

  Fly   473 AENGPMDMYNGTIAKLLAEDLQDMGSIILADDLESYEADVINSITMDLGDDTLYVVPPVSSGSVV 537
            |..||:..|.|:||..|..||:|.||.|..:||....|.:.::|.|.|.:..|::.||..||.|:
  Fly   246 ANEGPLSFYRGSIADDLLADLKDAGSAITKEDLNQAHAKLSSAIVMPLDEYDLHLTPPPGSGHVL 310

  Fly   538 AHVLAILQGYNFTAQDLSTEELKARTIHRFAEAMKFAFAQRPELGDMHFIDARELVSRLNSPDFG 602
            ..::.||:  .|.|:......:..|.||...|||||.|.:|.:|.:.   .:.||:|.|.|.:..
  Fly   311 GFIMNILK--EFRAEFSRAGTMSPRQIHLMVEAMKFGFVKRWQLDES---ASEELLSNLTSHELA 370

  Fly   603 DQNRAKINDSHVLPDAQAYGAN-FAAIEDLDGTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRT 666
            .....:||.:|.....:.|||: ...|.|..||::..||..| ||||||||||.|||||..|.||
  Fly   371 KSVARQINHTHTFNRPEFYGASPGIQIRDEHGTAHTSVLHGN-DAVSVTSSINFYFGSGRTGRRT 434

  Fly   667 GIVLNNGMNDFAVK--NNIFALP-QSQSNKIEAHKRAMSSQSPILLADK-DGNMKMVIGAAGGSK 727
            |::.||.|:||:::  .|.|.|| ...:|.:....|.|||..|:::.:: .||:::|:|||||:|
  Fly   435 GVIFNNAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIVTERATGNVRLVVGAAGGTK 499

  Fly   728 IIPAVVEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHKLKSISVK 792
            ||.|:..:...:||....::.|:||.|.:||::|:||.||. |..:|.:..|.:|||:.:... .
  Fly   500 IISALSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEY-GLRQSYVDSLAERGHRCERYE-N 562

  Fly   793 TGSVVTAISRNATAIYANADYRKRGGVAGF 822
            .|||:..|::....|:.|:|:||.|||:||
  Fly   563 RGSVICGIAQANDTIWVNSDFRKPGGVSGF 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	208/518 (40%)
CG1492	NP_001303553.1	G_glu_transpept	76..587	CDD:279371	208/518 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468967
Domainoid	1	1.000	319	1.000	Domainoid score	I669
eggNOG	1	0.900	-	-		E1_COG0405
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	249	1.000	Inparanoid score	I124
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		otm51323
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
	11	10.910