DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4829 and ggt2

DIOPT Version :9

Sequence 1:	NP_728030.2	Gene:	CG4829 / 32672	FlyBaseID:	FBgn0030796	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_593273.1	Gene:	ggt2 / 2543110	PomBaseID:	SPAC56E4.06c	Length:	611	Species:	Schizosaccharomyces pombe

Alignment Length:	550	Identity:	190/550 - (34%)
Similarity:	299/550 - (54%)	Gaps:	33/550 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 QHGAVSSDNLECSKIGSGILQKNGSAVDAAIAALLCNGLLTLQSMGIGGGHLMNVYNRKERHATA 352
            :.|||:|:...||.||..:|...|:|||||||:..|.|::...|.|||||..|.:.:..|. |.:
pombe    80 RRGAVASEVPVCSDIGVSMLADGGNAVDAAIASTFCIGVVNFFSSGIGGGGFMLIKHPNET-AQS 143

  Fly   353 IDAREVAPYEATEDMFAQQPENSDKGPLSIAVPGEVMGYHVAHQKFGQLPWAELVAPSLELCEKG 417
            :..||:||...::.||.:.|..:..||||||:|||:.|.:.|.:..|.|.|::|:.|:::|..:|
pombe   144 LTFREIAPGNVSKHMFDKNPMLAQVGPLSIAIPGELAGLYEAWKSHGLLDWSKLLEPNVKLAREG 208

  Fly   418 YHVSQHMERALDI-ALPYIKEHEQYQIYLNAETGKPHVAGTVVKPPKNLCKTYKLLAENGPMDMY 481
            :.|::.|||.|.: .:.::.:...:|..| ...||...||..:..|. ..||.:::|..|....|
pombe   209 FPVTRAMERVLKLPEMAHLLKDPIWQPIL-MPNGKVLRAGDKMFRPA-YAKTLEIIANKGIEPFY 271

  Fly   482 NGTIAKLLAEDLQDMGSIILADDLESYE---ADVINSITMDLGDDTLYVVPPVSSGSVVAHVLAI 543
            .|.:...:.:.:||.|.|:..:|..:|.   ||.::  |...|.| :|.....:||..:...|.|
pombe   272 RGELTNSMVKFIQDNGGIVTVEDFGNYSTVFADALH--TSYRGHD-VYTCTLPTSGPALIEGLNI 333

  Fly   544 LQGYNFTAQDLSTEELK-ARTIHRFAEAMKFAFAQRPELGDMHF--IDARELVSRLNSPDFGDQN 605
            |.||     .|:|..|. .:.:|...||||:..|.|.:.||..|  :|..::||:|.|.:|..|.
pombe   334 LDGY-----PLNTPSLAFPKRLHLEVEAMKWLSAGRTQFGDPDFLPLDHLDVVSKLLSKEFASQI 393

  Fly   606 RAKINDSHVLPDAQAYGANFAAIEDL---DGTSNLVVLAPNGDAVSVTSSINSYFGSGLIGPRTG 667
            |..|:.|...| .:.|..::    ||   .||:::..:..|..|||:||::|..|||.|:.|.||
pombe   394 RNNISLSKTYP-WEHYNPSY----DLPISHGTTHVSTVDSNNLAVSITSTVNLLFGSQLMDPVTG 453

  Fly   668 IVLNNGMNDFAV--KNNIFALPQSQSNKIEAHKRAMSSQSPILLADKDGNMKMVIGAAGGSKIIP 730
            :|.|:.|:||::  .:|.|.|..|..|.||..||..||.:|.:|.|.:|:.:|.:||:|||:|:.
pombe   454 VVFNDQMDDFSIPGASNAFNLSPSPWNFIEPFKRPQSSSAPTILTDINGDFEMALGASGGSRIVT 518

  Fly   731 AVVEVAANVLWFGKDLRQAVDAPRFYHQLMPDVLEYEEDGFTESLLQLLTKRGHK---LKSISVK 792
            ||::.....:....|:...|.:.|.:|||:||:| ..|.||::|:...:.|.|||   ||.....
pombe   519 AVLDSIIKRIDMDYDIESMVASARPHHQLLPDIL-ILESGFSKSVATRMKKYGHKVWRLKQHDTP 582

  Fly   793 TGSVVTAISRNATAIYANADYRKRGGVAGF 822
            . |.:.|::|:.:..|..:|.||.|..|.:
pombe   583 L-SQIQAVTRHHSEYYGMSDPRKYGQAAAY 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4829	NP_728030.2	G_glu_transpept	306..817	CDD:279371	180/525 (34%)
ggt2	NP_593273.1	G_glu_transpept	97..606	CDD:279371	180/526 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68450
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		mtm9265
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R489
SonicParanoid	1	1.000	-	-		X210
TreeFam	1	0.960	-	-
	12	11.810