Protein Alignment ppk28 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 632
• Identity: 136/632 - (21%)
• Similarity: 230/632 - (36%)
• Gaps: 145/632 - (22%)

  Fly    37 KRSVVYYLKNSTLHGLKYIAEESITIPER----IFFGLAFVLVVILSVFFISNVYVKWSASPIII 97
            |..:|:|..|:..||.|.|..|.   |::    ....|.|..:|..........|:.|..|   :
Human    42 KELLVWYCDNTNTHGPKRIICEG---PKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVS---V 100

  Fly    98 STSAKQKLTSNMPFPAITICNLN-------QALLSKVDRIGRTSTNFSLLMGLCDQGGDTTISYI 155
            |.|...|   .|.|||:||||.:       :.||..:|.:........|...|........:::
Human   101 SLSVGFK---TMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNF- 161

  Fly   156 GTWKYFKAILVDVAQPCEKMLLYCSFGSREEDCSWLFTSILTDDGLC-----------CNFNALH 209
            ..|.:...:|:|...|...|:|.. ||.....    .||....:.:|           |:.|...
Human   162 SIWNHTPLVLIDERNPHHPMVLDL-FGDNHNG----LTSSSASEKICNAHGCKMAMRLCSLNRTQ 221

  Fly   210 PSYLIRNYSDDVR----------------------LETAHPNTRYELID-WTPEKGYARNLPEFY 251
            .::  ||::...:                      :|.::|..:..|.. :..|....||....:
Human   222 CTF--RNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIF 284

  Fly   252 FPR----------------TSGGTGIRMGLTVVLNASIAEYYCTKSMSVGFKVLVHNPAELPKVS 300
            :|.                .|...|...||.::|:....:|....:.:.|.::::|.....|.:.
Human   285 YPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIR 349

  Fly   301 NYGFVVTAGREARIPI---------EPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNC 356
            :.|....:|.|..|.:         || |...  |:...:..|:. .:||     |..|||.:.|
Human   350 DEGIYAMSGTETSIGVLVDKLQRMGEP-YSPC--TVNGSEVPVQN-FYSD-----YNTTYSIQAC 405

  Fly   357 ELECEAKLLLRECSC--VLYYLPRIDPLARVCG----PNDNQCTDRVQTEIESSLTNLSCENCWP 415
            ...|....::|.|:|  .||.|||.:   :.|.    |:...|...:|..:....|.:..  |..
Human   406 LRSCFQDHMIRNCNCGHYLYPLPRGE---KYCNNRDFPDWAHCYSDLQMSVAQRETCIGM--CKE 465

  Fly   416 GCFELTYRATLSTASIVSDPRFQAGENLPEYIFH---GPYSNASEISI-------LHFYYMTNIF 470
            .|.:..|:.|:|.|...|    :|.|   ::|||   .....::.|::       |:.|:....:
Human   466 SCNDTQYKMTISMADWPS----EASE---DWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNY 523

  Fly   471 RSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRRLEQLSWL 535
            |:..:|........|||.||..|.:||.|:..:|| |..|.:                  ...|:
Human   524 RTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIE-FGEIII------------------DFVWI 569

  Fly   536 TPIRM-PVRRALRRNRGGLLRNPPPPAYSDLQKFRGKLD-KPETCKR 580
            |.|:: .:.::||:.|.......|||..::|.:...... :|:|..|
Human   570 TIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPR 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	120/551 (22%)
SCNN1B	XP_016879014.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152139
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40930
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.650