Protein Alignment ppk28 and asic1c

DIOPT Version :10

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_021325802.1
• Gene: asic1c / 407670
• ZFINID: ZDB-GENE-040513-3
• Length: 562
• Species: Danio rerio
• Alignment Length: 674
• Identity: 147/674 - (21%)
• Similarity: 232/674 - (34%)
• Gaps: 228/674 - (33%)

  Fly     5 TESRRRQSGSSGCKKDSESDDDENTICSRAAIKRSVVYYLKNST--------LHGLKYIAEESIT 61
            |.:|......|.|:|                :|.::.:.:|:.|        :||||:......:
Zfish    11 TINRHEAQSPSSCRK----------------LKMTLTHNIKDITTAFVLRTKVHGLKHAFSPHKS 59

  Fly    62 IPERIFFGLAFVLVVILSVFF---------------ISNVYVKWSASPIIISTSAKQKLTSNMPF 111
            ..:|:|:.||  |:|.|.:.|               ::.:|:.||               :||.|
Zfish    60 KTQRLFWLLA--LLVCLGLLFTWSWNRILYLLSYPAVTKIYMVWS---------------NNMTF 107

  Fly   112 PAITICNLNQALLSKVDR------------------IGRTST----------------NFSLLMG 142
            ||||.||.|:..:|.:.|                  :.|.|.                :||....
Zfish   108 PAITFCNQNRLRVSSLTRDDLYYSGYWMDILHLNHTLNRQSVSMLKHSRHRERLLHLLDFSHYSP 172

  Fly   143 LCDQGGDTTISYIGTWKYFKAILVD-VAQPCEKMLLYCSFGSREEDCSWL-FTSILTDDGLCCNF 205
            ..||..:||            .::| :....:.|||.|.|  |.|:|::. ||.|.|..|.|..|
Zfish   173 PPDQSLNTT------------EMIDRLGHQLQDMLLECRF--RGENCTYKNFTPIYTRYGKCYTF 223

  Fly   206 NALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPRTSGGTGIRMGLTVVLN 270
            |:                          .:|..|           ......||||  .||.::|:
Zfish   224 NS--------------------------GLDGNP-----------LLTTLKGGTG--NGLEIMLD 249

  Fly   271 ASIAEYYCT------KSMSVGFKVLVHNPAELPKVSNYGFVVTAG--------REARIPIEPVYE 321
            ....||...      .|...|.||.:|:..|.|.:...||.|..|        ::..:.:.|.:.
Zfish   250 IQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWG 314

  Fly   322 DALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCVLYYLPRIDPLARVC 386
            |..               |...|..|:.|||...|.::||.:.||..|:|.:.::|   ..:.||
Zfish   315 DCR---------------SAPMDSEYFSTYSITACRIDCETRYLLENCNCRMVHMP---GTSTVC 361

  Fly   387 GPND-NQCTD-RVQTEIESSLTNLSCENCWPGCFELTYRATLSTASIVSD-------PRFQAGEN 442
            .|.. ..|.| .:...:|.......|:.   .|....|...||...|.|.       .:|...|
Zfish   362 TPEQYKDCADPALDFLVEKDNDYCVCDT---PCNMTRYGKELSMVKIPSKASAKYLAKKFNKTE- 422

  Fly   443 LPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIF 507
              :||       ...|.:|..::....:....:.:.:.....|.:.||.:|||:|.|:.:::|||
Zfish   423 --QYI-------TDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIF 478

  Fly   508 FYI--TVRPYCASRTLRQR--HKRRLEQLSWLTPIRMPVRRALRRNRGGLLRNPPPPAYSD---- 564
            .|:  .::.......||:|  |:...:.|.:......|          |:..| ..|::.|
Zfish   479 DYLYEVLKDKILGSVLRKRRPHRSASDNLDFSENPTSP----------GVTSN-HVPSFHDGDDV 532

  Fly   565 LQKFRGKL----------DKPETC 578
            |||||...          |...||
Zfish   533 LQKFRAHATHSGVTRTASDSRRTC 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:459966	122/547 (22%)
asic1c	XP_021325802.1	ENaC	34..531	CDD:273304	133/608 (22%)