Protein Alignment ppk28 and asic4a

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_999952.1
• Gene: asic4a / 407668
• ZFINID: ZDB-GENE-040513-5
• Length: 539
• Species: Danio rerio
• Alignment Length: 590
• Identity: 128/590 - (21%)
• Similarity: 232/590 - (39%)
• Gaps: 116/590 - (19%)

  Fly     6 ESRRRQSGSSGCKKDSESDDDENTICSRAAIKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGL 70
            |...:|.|:....|:|..::.    ||...  :.:..:...|:|||:.:|.........:..:.|
Zfish    13 EEDEKQKGNQDGDKESLIEES----CSPPT--KDLAGFASASSLHGINHIFVSGRLGVRQTLWAL 71

  Fly    71 AFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLNQ---ALLSKVDRIGR 132
            ||::.:.|.::..:...:.:...|.:  |:..::.|..|.|||:||||:|:   :.|:..|
Zfish    72 AFLVSLALFLYQAAKCAISYLEHPHV--TALNEEATPEMVFPAVTICNINRFRFSALTDAD---- 130

  Fly   133 TSTNFSLLMGLCDQGGD----TTISYIGTWKYFKAILVDVAQPCEKMLLYCSFGSRE---EDCSW 190
             ..:.:.|.||..:..|    |.:.|..  ...:.|........|:||..|:|..:.   ||
Zfish   131 -IYHLANLTGLPPKNKDGHKPTDLEYPA--PDMQDIFNRTGHQLEEMLKSCNFSGQNCSAED--- 189

  Fly   191 LFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPRT 255
             ||.:.|..|.|..||.               .:|....|:
Zfish   190 -FTVVYTRYGKCYTFNG---------------NKTTSRKTK------------------------ 214

  Fly   256 SGGTGIRMGLTVVLNASIAEYY------CTKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARI 314
            .||.|  .||.::|:....:|.      ...|:..|.:|.:|:..|.|.:...||.|:.|.:..:
Zfish   215 QGGMG--NGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFV 277

  Fly   315 PIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCVLYYLPRI 379
            ..:......||      :....|..:.|..:..|.|||...|.|.||...:||||.|.:.::|..
Zfish   278 SCQEQRLTYLP------QPWGNCRSTSEQMIPGYDTYSISACRLRCETLEVLRECKCRMVHMPGD 336

  Fly   380 DPLARVCGPNDNQCTDRVQTEIESSLTNLSCENCW--PGCFELTYRATLSTASIVS-------DP 435
               |.:|.|:|.:|.|:....::.|    |.:.|:  ..|....|...||...|.|       ..
Zfish   337 ---ANICTPSDIKCVDKALALLQKS----SGDTCFCETPCNLTRYGKELSMVKIPSKGSARYLSR 394

  Fly   436 RFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSI 500
            ::...|   :||       .....:|..::....:.:..:.:.:.....|.:.||.:|||:|.|:
Zfish   395 KYDKSE---DYI-------RDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASV 449

  Fly   501 FSVIEIFFYI-TVRPYCASRTLR-----QRHKRRLEQLSWLTPIRMPVRRALRRNRGGLLRNPPP 559
            .:::||..|: .|..:...|.||     ::..::.:|.|.:..:.:...:|  ::...:.|:...
Zfish   450 LTILEILDYVYEVIKHRLERLLRPQRDDKKQTQQQQQASTVATVNLEEMKA--KDSSEMSRSHSE 512

  Fly   560 PAYSD 564
            .||::
Zfish   513 GAYAN 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	110/490 (22%)
asic4a	NP_999952.1	ASC	44..472	CDD:295594	113/504 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	474..494		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586636
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26596
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3633
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.830