Protein Alignment ppk28 and Asic2

DIOPT Version :10

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 113/542 - (20%)
• Similarity: 186/542 - (34%)
• Gaps: 172/542 - (31%)

  Fly    44 LKNSTLHGLKYIAEESI----TIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQK 104
            |..:.||||:::.....    :...|..:.|||...:.|.:.:.||..:.|.:.|  ..|...::
  Rat    61 LSRTKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSLGLLLSWSSNRLLYWLSFP--SHTRVHRE 123

  Fly   105 LTSNMPFPAITICNLNQALLSKVDRIGRTSTNFSLLMGLCDQGGDTTISYIGTW----------- 158
            .:..:||||:|:||.|.....::.:                  ||  :.|.|.|
  Rat   124 WSRQLPFPAVTVCNNNPLRFPRLSK------------------GD--LYYAGHWLGLLLPNRTAR 168

  Fly   159 -----------------------------KYFKAI---LVD-VAQPCEKMLLYCSFGSREEDCS- 189
                                         ::|:.|   .:| :....|.|||.|.:  |.|.|.
  Rat   169 PLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKY--RGELCGP 231

  Fly   190 WLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPR 254
            ..|:|:.|..|.|         |:..:..|...|.|.
  Rat   232 HNFSSVFTKYGKC---------YMFNSGEDGKPLLTT---------------------------- 259

  Fly   255 TSGGTGIRMGLTVVLNASIAEYYC------TKSMSVGFKVLVHNPAELPKVSNYGFVVTAG---- 309
            ..||||  .||.::|:....||..      ..:...|.||.:|:.:|.|.:...||.|..|
  Rat   260 VKGGTG--NGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTF 322

  Fly   310 ---REARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSC 371
               :|.|:...|      |.....:        |.|..|.::..||...|.::||.:.::..|:|
  Rat   323 VATQEQRLTYLP------PPWGECR--------SSEMGLDFFPVYSITACRIDCETRYIVENCNC 373

  Fly   372 VLYYLPRIDPLARVCGPNDNQCTDRVQTEIESSLTNLSCEN------CWPGCFELTYRATLSTAS 430
            .:.::|...|.          ||.....|.......|..|.      |...|....|...||...
  Rat   374 RMVHMPGDAPF----------CTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVK 428

  Fly   431 IVS-------DPRFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNT 488
            |.|       :.:|...|   :||       :..|.:|..::....:.:..:.:.:.....|.:.
  Rat   429 IPSKTSAKYLEKKFNKSE---KYI-------SENILVLDIFFEALNYETIEQKKAYEVAALLGDI 483

  Fly   489 GGLLGLFMGFSIFSVIEIFFYI 510
            ||.:|||:|.|:.:::|:|.||
  Rat   484 GGQMGLFIGASLLTILELFDYI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:459966	111/539 (21%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	112/539 (21%)