Protein Alignment ppk28 and Scnn1g

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_058742.2
• Gene: Scnn1g / 24768
• RGDID: 3641
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 667
• Identity: 158/667 - (23%)
• Similarity: 224/667 - (33%)
• Gaps: 184/667 - (27%)

  Fly    36 IKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPII---- 96
            ||..:.:|..|:..||.:.|......:  |....:||.|..:..:.        |..:.::
  Rat    25 IKDLMHWYCMNTNTHGCRRIVVSRGRL--RRLLWIAFTLTAVALII--------WQCALLVFSFY 79

  Fly    97 -ISTSAK---QKLTSNMPFPAITICNLNQALLSKV-----DRIGRTSTNFSLLMGLCD-----QG 147
             :|.|.|   |||    .|||:||||:|....|.|     |....|......|.|:.:     :.
  Rat    80 TVSVSIKVHFQKL----DFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKESRKRREA 140

  Fly   148 GDTTISYIGT-WKYFKAILVDVAQPCEKMLLYCSFGSREEDCSWLF------------TSILTDD 199
            |....:..|| .::||.|.:.|....||......|..|:...|...            :..|...
  Rat   141 GSMPSTLEGTPPRFFKLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGF 205

  Fly   200 GLCCN-------------FNALHPSYLIR--NYSDDVRLETAHPNTRY---ELIDWTPEKGY--- 243
            .||.|             .||:...|.:.  |....|.|| ...|..|   ||:......|.
  Rat   206 QLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLE-KKINMSYSAKELLVTCFFDGMSCD 269

  Fly   244 ARNLPEFYFP-----------------RTSGGTGIRMGLTVVLNASIAEYYCTKSMSVGFKVLVH 291
            |||...|:.|                 .||.| |...||.|:|..:..||......|.|.|||:|
  Rat   270 ARNFTLFHHPMYGNCYTFNNKENATILSTSMG-GSEYGLQVILYINEDEYNPFLVSSTGAKVLIH 333

  Fly   292 NPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDL----AYYRTYS 352
            ...|.|.:.:.|..:.......|.:.      |.....:.:...:|. .|.:|:    .|...||
  Rat   334 QQNEYPFIEDVGMEIETAMSTSIGMH------LTESFKLSEPYSQCT-EDGSDVPVTNIYNAAYS 391

  Fly   353 RKNCELECEAKLLLRECSCVLYYLPRIDPLARVCG----PNDNQCTDRV-QTEIESSLTNLSCEN 412
            .:.|...|....::.:|.|..|..| :.|.|..|.    ||...|..:: |..:..   .|.|::
  Rat   392 LQICLYSCFQTKMVEKCGCAQYSQP-LPPAANYCNYQQHPNWMYCYYQLYQAFVRE---ELGCQS 452

  Fly   413 -CWPGCFELTYRATLSTAS-------------IVSDPRFQAGENLPEYIFHGPYSNASEISILHF 463
             |...|....:..|.|.|.             :..|...|..:.|          |.::::.|..
  Rat   453 VCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKL----------NKTDLAKLLI 507

  Fly   464 YYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEI-------FFYITVRPYCASRTL 521
            :|.....||..:|........|||.||.|||:|..|:..||||       ||.|..|
  Rat   508 FYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIAR-------- 564

  Fly   522 RQRHK------RRLEQLSWLTP-----------------------IRMPVRRALRRNRGGLLRNP 557
            ||.||      ||....|..||                       :|:|..      .|..:...
  Rat   565 RQWHKAKDWWARRQTPPSTETPSSRQGQDNPALDTDDDLPTFTSAMRLPPA------PGSTVPGT 623

  Fly   558 PPPAYSDLQKFRGKLDK 574
            |||.|:.|     :||:
  Rat   624 PPPRYNTL-----RLDR 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	134/564 (24%)
Scnn1g	NP_058742.2	ENaC	24..631	CDD:273304	155/656 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..628		10/56 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345666
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4773
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.700