Protein Alignment ppk28 and Scnn1g

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_035456.1
• Gene: Scnn1g / 20278
• MGIID: 104695
• Length: 655
• Species: Mus musculus
• Alignment Length: 680
• Identity: 154/680 - (22%)
• Similarity: 223/680 - (32%)
• Gaps: 206/680 - (30%)

  Fly    36 IKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPII---- 96
            ||..:.:|..|:..||.:.|......:  |....:||.|..:..:.        |..:.::
Mouse    25 IKDLMHWYCLNTNTHGCRRIVVSRGRL--RRLLWIAFTLTAVALII--------WQCALLVFSFY 79

  Fly    97 -ISTSAK---QKLTSNMPFPAITICNLNQALLSKV-----DRIGRTSTNFSLLMGLCD------- 145
             :|.|.|   |||    .|||:||||:|....|.|     |....|......|.|:.|
Mouse    80 TVSVSIKVHFQKL----DFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPR 140

  Fly   146 ---QGGDTTISYIGTWKYF----------------------------------KAILVDVAQPCE 173
               :.|....::.||...|                                  ||..|......:
Mouse   141 KRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESK 205

  Fly   174 KMLLYCSFGSREEDC-SWLFTSILTDDGLCCNFNALHPSYLIR--NYSDDVRLETAHPNTRY--- 232
            |::.:....:...|| ::.|:|         ..||:...|.:.  |....|.|| ...|..|
Mouse   206 KLVGFQLCSNDTSDCATYTFSS---------GINAIQEWYKLHYMNIMAQVPLE-KKINMSYSAE 260

  Fly   233 ELIDWTPEKGY---ARNLPEFYFP-----------------RTSGGTGIRMGLTVVLNASIAEYY 277
            ||:......|.   |||...|:.|                 .||.| |...||.|:|..:..||.
Mouse   261 ELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMG-GSEYGLQVILYINEDEYN 324

  Fly   278 CTKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDE 342
            .....|.|.|||||...|.|.:.:.|..:.......|.:.      |.....:.:...:|. .|.
Mouse   325 PFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMH------LTESFKLSEPYSQCT-EDG 382

  Fly   343 NDL----AYYRTYSRKNCELECEAKLLLRECSCVLYYLPRIDPLARVCG----PNDNQCTDRV-Q 398
            :|:    .|...||.:.|...|....::.:|.|..|..| :.|.|..|.    ||...|..:: |
Mouse   383 SDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQP-LPPAANYCNYQQHPNWMYCYYQLYQ 446

  Fly   399 TEIESSLTNLSCEN-CWPGCFELTYRATLSTAS-------------IVSDPRFQAGENLPEYIFH 449
            ..:..   .|.|:: |...|....:..|.|.|.             :..|...|..:.|
Mouse   447 AFVRE---ELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKL------ 502

  Fly   450 GPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEI-------F 507
                |.::::.|..:|.....||..:|........|||.||.|||:|..|:..||||       |
Mouse   503 ----NKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDF 563

  Fly   508 FYITVRPYCASRTLRQRHKRRLEQLSWLTPIRMPVRRALRRNRGGLLRNPPPPAYSDLQKFRGKL 572
            |.|..|        ||..|.:    .|.         |.||.         ||:.......:|
Mouse   564 FSIIAR--------RQWQKAK----DWW---------ARRRT---------PPSTETPSSQQG-- 596

  Fly   573 DKPETCKRKLWRTLQVRPVVDRADEELPTY 602
                          |..|.:| .|::|||:
Mouse   597 --------------QDNPALD-TDDDLPTF 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	132/578 (23%)
Scnn1g	NP_035456.1	ENaC	24..636	CDD:273304	154/680 (23%)
		deg-1	32..557	CDD:273309	131/570 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..636		12/56 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842236
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650