Protein Alignment ppk28 and asic-2

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 112/521 - (21%)
• Similarity: 200/521 - (38%)
• Gaps: 127/521 - (24%)

  Fly    47 STLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPF 111
            ||:..:.::|..:..| .|||:...|:.|:.:..:.:..:..|:.:.|..::|   :.|.....|
 Worm    17 STVAVVPHVANANNKI-SRIFWIAIFLFVLGMFAYELYILIAKFFSYPATVNT---EILFEKQIF 77

  Fly   112 PAITICNLNQALLSKVDRIGRTSTNFSLLMGLCDQGGDTTISYIGT--WKYF------------- 161
            |.:|:||:|....|.|    ::::.||.:..|.....|.|:....|  |..:
 Worm    78 PVVTVCNMNPYKYSVV----KSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRA 138

  Fly   162 -KAILVD---VAQPCEKMLLYCSFGSREEDCSWL--------FTSILTD-DGLCCNFNALHPSYL 213
             .|::::   ::...:...|| ::....:|||:.        ||..:.. .|.|.:||
 Worm   139 ADALVLEANLISDTAKVPALY-TYADLIQDCSFAGIPCSESDFTKFIDPVYGACYSFN------- 195

  Fly   214 IRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPRTSGGTGIRMGLTVV---LNASIAE 275
                 :|..|                  .|:.:.....|       |:::.|||.   .|.:...
 Worm   196 -----EDASL------------------NYSVSREGIQF-------GLKLMLTVTQTKTNGNTDS 230

  Fly   276 YYCTKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFS 340
            ...||  ..|.::.|::....|.:.:.|.....|.|:.:.:     .....:|: ||....|:..
 Worm   231 LPTTK--LAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSV-----SLTQNVRA-KKPYGTCVDR 287

  Fly   341 DENDLAYYR--TYSRKNCELECEAKLLLRECSCVLYYLPRIDPLARVCGPNDNQC------TDRV 397
            :.:...||:  .|:.:.|...|:.:..:.:|.|.   .||:     ..|..|..|      .|.:
 Worm   288 EPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCA---NPRL-----ALGSTDTACQPIKADLDCL 344

  Fly   398 QT---EIESSLTNL----SCENCWPGCFELTYRATLSTASIVSDPRFQAGENLPEYIFHGPYSNA 455
            ||   ...||..|:    .| ||.|.|.|.||..|:|.|...|...:.|..:....   |..|:.
 Worm   345 QTLKGNQTSSTPNIDLLVEC-NCNPPCDESTYTPTVSLAQFPSTSYYVATSSTAGV---GSCSST 405

  Fly   456 ----SEISILHFYYMTN-----IFRSTTKSEMF----GFT--EFLSNTGGLLGLFMGFSIFSVIE 505
                |..|....:|..|     :|..|...|::    |:|  ..:::.||..||::|.|:.||:|
 Worm   406 NSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLGLSVISVVE 470

  Fly   506 I 506
            :
 Worm   471 M 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	112/521 (21%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	112/521 (21%)
		ASC	13..471	CDD:279230	111/519 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7217
OMA	1	1.010	-	-		QHG28677
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.680