DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk28 and delm-1

DIOPT Version :9

Sequence 1:	NP_573169.2	Gene:	ppk28 / 32671	FlyBaseID:	FBgn0030795	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_501590.2	Gene:	delm-1 / 184882	WormBaseID:	WBGene00009073	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	575	Identity:	122/575 - (21%)
Similarity:	209/575 - (36%)	Gaps:	152/575 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ENTICSRAAIKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWS 91
            |.||    ::||...::.:.:|:||.|.|.:     .:|||..|.::::|:.|:..:  :|..|.
Worm    61 EGTI----SVKRETQHFCETTTMHGPKRIFK-----GKRIFTKLFWLIMVLGSLGLL--IYQCWI 114

  Fly    92 ASPIIISTSAKQKLT-----SNMPFPAITICNLNQALLSKVDRIGRTS--------------TNF 137
            .|...:|.....:::     ..|.||::|:||......|.::.:.||.              |..
Worm   115 LSASYLSKPIVSQVSFLIPEDGMEFPSVTVCNFTPIRKSYIEAMNRTGDVSPDMINYLMNWFTEI 179

  Fly   138 SLLMGLCDQ-----GGDTTISYIGTWKYFKA--ILVDVAQPCEKMLLYCSFGSREEDCSWLFTSI 195
            .:|:|..||     |.:....|......|..  ..:|.:..|..::..|||.....||..|.:..
Worm   180 PILLGNTDQQSLNKGNEELREYQSIHPNFTVDQFFMDASFDCSDLMKLCSFQGESFDCCSLASPT 244

  Fly   196 LTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPRTSGGTG 260
            ||..|.|...:                |..:..|.:.|                         .|
Worm   245 LTPVGKCFTLD----------------LSKSPMNKQTE-------------------------PG 268

  Fly   261 IRMGLTVVLNASIAEYY---------CTKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPI 316
            ||.||::.|:|::.|.:         ...|...||:..||....:|.:::..:.|:....|...|
Worm   269 IRAGLSLTLDANLDEQFDSSTGIDALLPNSFVNGFRYFVHPKDTIPNLASDEYTVSPNSVAYSAI 333

  Fly   317 EPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSC--VLYYLPRI 379
            .......||     ......|.......:....:|:..||...|:||..:.:|.|  .||.:
Worm   334 SKFRYVLLP-----PNDWGNCTEDYPYGIQSNLSYTSGNCLSLCKAKYFMNQCGCTPALYNI--- 390

  Fly   380 DPLARVCGPNDNQCTD-RVQTEIESSLTNL------------SCENCWPGCFELTYRATLSTASI 431
                   |.|..:||. .....:.:||:.|            ||..|...|....|||..|..:
Worm   391 -------GNNFQECTPFETYNCVNNSLSLLNEETGKMEFQPPSCTRCGQQCDSQVYRADNSNGN- 447

  Fly   432 VSDPRFQAGENLPEYIFHGPYSNA-----------SEISILHFYYMTNIFRSTTKSEMFGFTEFL 485
                :|.||      .|:  |.|:           |...::..:|....:....:.:....|:.|
Worm   448 ----QFSAG------AFN--YFNSKNSSWSVDYMKSNFQMIRIFYRDMSYTEYNQVQDASITDLL 500

  Fly   486 SNTGGLLGLFMGFSIFSVIEIFFYI----------TVRPYCASRTLRQR-HKRRL 529
            |..||.:|:|:|.|:.:::|:|.:.          |.|.|..|:...:: ||:.:
Worm   501 SAIGGNMGMFLGGSVITIVELFLFFSKVFWIGFSKTRRNYLYSKRANEKAHKKEV 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	111/526 (21%)
delm-1	NP_501590.2	ASC	73..524	CDD:279230	111/526 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28677
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14160
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760