Protein Alignment ppk28 and mec-4

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 753
• Identity: 143/753 - (18%)
• Similarity: 229/753 - (30%)
• Gaps: 282/753 - (37%)

  Fly    13 GSSGCKKDSESDDDENTICSRAAIK-----RSVVYYLK----NSTLHGLKYIAEESITIPERIFF 68
            |...|...:||:.....|......|     :.:.::.|    .::.||:..|. |:..:..|..:
 Worm    48 GYGECFNSTESEVQCELITGEFDPKLLPYDKRLAWHFKEFCYKTSAHGIPMIG-EAPNVYYRAVW 111

  Fly    69 GLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLN---QALLSKVDRI 130
            .:.|:..:|:......:|..|::.:..|:....|   ....||||||:||||   .:|.:.||.:
 Worm   112 VVLFLGCMIMLYLNAQSVLDKYNRNEKIVDIQLK---FDTAPFPAITLCNLNPYKASLATSVDLV 173

  Fly   131 GRTSTNFSLLMG-------------------------------------------------LCDQ 146
            .||.:.|...||                                                 ||..
 Worm   174 KRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTTPAPTTKPARRRGKRDLSGAFFEPGFARCLCGS 238

  Fly   147 GG----------------DTTISYIGTWKYFKAILVDVAQPCEKMLLY----------------- 178
            .|                :||     |.|.|.  :.|..:..:.|..|
 Worm   239 QGSSEQEDKDEEKEEELLETT-----TKKVFN--INDADEEWDGMEEYDNEHYENYDVEATTGMN 296

  Fly   179 -----------------------CSFGSREEDC-------SWLFT--------SILTDDG----- 200
                                   |:|.....|.       :|..|        :..|.|.
 Worm   297 MMEECQSERTKFDEPTGFDDRCICAFDRSTHDAWPCFLNGTWETTECDTCNEHAFCTKDNKTAKG 361

  Fly   201 -----------LCCNFNALHPSYLIRNY---------------------SDDVRLET-AHPN--- 229
                       .|..:|...|...|..|                     :|:|.:.| |..|
 Worm   362 HRSPCICAPSRFCVAYNGKTPPIEIWTYLQGGTPTEDPNFLEAMGFQGMTDEVAIVTKAKENIMF 426

  Fly   230 ---------------TRYELIDWTPEKGYARNLP---------------EFYFPRTSGGTGIRMG 264
                           |:.||:......|.|.::.               .|...||...|.||.|
 Worm   427 AMATLSMQDRERLSTTKRELVHKCSFNGKACDIEADFLTHIDPAFGSCFTFNHNRTVNLTSIRAG 491

  Fly   265 ------LTVVLNASIAEYYCTKSMSVGFKVLVHNPAELPKVSNYGFVVTAG----------REAR 313
                  :.|.:|||   .|...:.:.|.::.:|:..:.|....:|:....|          :.:|
 Worm   492 PMYGLRMLVYVNAS---DYMPTTEATGVRLTIHDKEDFPFPDTFGYSAPTGYVSSFGLRLRKMSR 553

  Fly   314 IPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYR-TYSRKNCELECEAKLLLRECSC--VLYY 375
            :|..  |.|.:|..::             :|..|.. .||.:.|...|..:|:|:||.|  ..:.
 Worm   554 LPAP--YGDCVPDGKT-------------SDYIYSNYEYSVEGCYRSCFQQLVLKECRCGDPRFP 603

  Fly   376 LPR-------IDPLARVCGPNDNQCTDRVQTEIESSLTNLSCENCWPGCFELTYRATLSTASIVS 433
            :|.       .||:||       :|.|....::.....:..| .|...|.:..|..|.|.|...|
 Worm   604 VPENARHCDAADPIAR-------KCLDARMNDLGGLHGSFRC-RCQQPCRQSIYSVTYSPAKWPS 660

  Fly   434 -DPRFQAG-------ENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGG 490
             ..:.|.|       |....|     ..|.:.:.:  ||...| |...|:||.:||...|::.||
 Worm   661 LSLQIQLGSCNGTAVECNKHY-----KENGAMVEV--FYEQLN-FEMLTESEAYGFVNLLADFGG 717

  Fly   491 LLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRR 528
            .|||:.|.|..:..|..|......|.::......:|::
 Worm   718 QLGLWCGISFLTCCEFVFLFLETAYMSAEHNYSLYKKK 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	134/697 (19%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	133/694 (19%)
		ASC	87..>172	CDD:279230	23/88 (26%)
		ASC	<428..739	CDD:295594	77/344 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162325
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650