Protein Alignment ppk28 and unc-8

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001294293.1
• Gene: unc-8 / 177494
• WormBaseID: WBGene00006748
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 731
• Identity: 137/731 - (18%)
• Similarity: 222/731 - (30%)
• Gaps: 279/731 - (38%)

  Fly     2 RTLTESRRRQSGSS----------GCKKDSESDDD-----------ENTICSRAAIKRSVVYY-- 43
            |.:.|....:|.||          |.....|.:||           |....||.:::...:.|
 Worm    34 RLVHEPESMESRSSPYIRPSPYAGGVHPHFEEEDDRSKLHASALYSERRTSSRKSLRSQKIDYHT 98

  Fly    44 --LKN--------STLHGLKYIAEESITIPERIFFG--------LAFVLVVILSVFFISNVYVKW 90
              :|:        ::.||:.|:|..|       |||        :..::..:|..::..:.|:::
 Worm    99 TTIKSLWFDFCARTSSHGIPYVATSS-------FFGRYVWAALFMCMLMAFLLQTYWTMSEYLQY 156

  Fly    91 SASPIIISTSAKQKLTSNMPFPAITICNLNQALLSKVDRIGRTSTNFS---------LLMGLCDQ 146
            ..   ||....:.:..:   |||.|:||||....|::.:.......|.         ::......
 Worm   157 RT---IIEMQLQFEAAA---FPAATVCNLNAFKYSELTQYEEIKEGFDYWERVINARMMSDSMKP 215

  Fly   147 GGDTTISYIGTWK---------------------YFKAILV------------------------ 166
            ||| .:..|...|                     .::.:.|
 Worm   216 GGD-ILEAISVRKKRSKSRDQLLFPIDDEDLEGAVYQPVFVRCTCMNMEQCVPNRNPLEVNASIC 279

  Fly   167 ----DVAQ----PCEKMLLY----CSFGSREEDCSWLFTSILTDDG----------------LCC 203
                ||.:    ||....::    ||..|....|.       ..||                ||.
 Worm   280 MCFEDVTRGLIWPCYPTSVWTVKKCSGCSISNTCP-------DPDGPNASKQIAKHNSPLPCLCQ 337

  Fly   204 NFN---ALHPSYLIR-----NYS---------------------DDVR---------------LE 224
            :.:   .:||...||     ||:                     .|::               |.
 Worm   338 SISHHCMVHPKDEIRWWNPNNYTVYSVTEPPTTEITETEEAFGLSDLKDAGAITTQTKENLIFLV 402

  Fly   225 TAHP-----NTRYELIDWT---------------------PEKGYARNLPEFYFPRT----SGGT 259
            .|.|     |..|.|.::.                     ||.|   |...|.|..:    :...
 Worm   403 AALPRETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYG---NCYTFNFNDSVELKNSRA 464

  Fly   260 GIRMGLTVVLNASIAEYYCTKSMSVGFKVLVHNPAELPKVSNYGFVVTAG---------REARIP 315
            |...||.::||...::|..| :.:.|.:::||...:.|....:|:....|         :|....
 Worm   465 GPMYGLRLLLNVHQSDYMPT-TEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRL 528

  Fly   316 IEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCVLYYLPRID 380
            ..| :.:...|.|.:             ...|...||.:.|...|....:|..|.|.....|...
 Worm   529 SAP-WGNCSDTFRPV-------------PYIYNEHYSPEGCHRNCFQLKVLEICGCGDPRFPLPS 579

  Fly   381 PLARVCGPN---DNQCTDRVQTEIESSLTNLS---------CENCWPGCFELTYRATLSTASIVS 433
            ...|.|...   |.||.        |:||:.|         || |...|.|..:. |..:||...
 Worm   580 EEHRHCNAKSKIDRQCL--------SNLTSDSGGYHHLHEQCE-CRQPCHEKVFE-TAYSASAWP 634

  Fly   434 DPRFQAGENLPEY--IFHGPYS-------NASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTG 489
            ...|:.|.:.|..  ||:...:       |.:.|.|   ||....|.|..::..:......|:.|
 Worm   635 SQNFKIGTDCPAVSDIFNDTEACTEYYRQNTAYIEI---YYEQLNFESLKETAGYTLVNLFSDFG 696

  Fly   490 GLLGLFMGFSIFSVIE 505
            |.:||::|||:.:..|
 Worm   697 GNIGLWIGFSVITFAE 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	125/669 (19%)
unc-8	NP_001294293.1	ASC	100..719	CDD:295594	124/665 (19%)
		deg-1	107..716	CDD:273309	123/658 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820